Diabetes and infection: review of the epidemiology, mechanisms and principles of treatment
An association between diabetes and infection has been recognised for many years, with
infection being an important cause of death and morbidity in people with diabetes. The …
infection being an important cause of death and morbidity in people with diabetes. The …
Favorable antiviral effect of metformin on SARS-CoV-2 viral load in a randomized, placebo-controlled clinical trial of COVID-19
CT Bramante, KB Beckman, T Mehta… - Clinical Infectious …, 2024 - academic.oup.com
Background Metformin has antiviral activity against RNA viruses including severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be …
respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be …
[HTML][HTML] Metformin reduces sars-cov-2 in a phase 3 randomized placebo controlled clinical trial
Current antiviral treatment options for SARS-CoV-2 infections are not available globally,
cannot be used with many medications, and are limited to virus-specific targets. 1–3 …
cannot be used with many medications, and are limited to virus-specific targets. 1–3 …
Diabetes Mellitus and Pneumococcal Pneumonia
C Cilloniz, A Torres - Diagnostics, 2024 - mdpi.com
Currently, there are more than 500 million people suffering from diabetes around the world.
People aged 65 years or older are the most affected by this disease, and it is estimated that …
People aged 65 years or older are the most affected by this disease, and it is estimated that …
Favorable antiviral effect of metformin on severe acute respiratory syndrome coronavirus 2 viral load in a randomized, placebo-controlled clinical trial of coronavirus …
CT Bramante, KB Beckman, T Mehta… - Clinical Infectious …, 2024 - academic.oup.com
Background Metformin has antiviral activity against RNA viruses including severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be …
respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be …
Metformin and infections: what is the next step in this decades-long story?
M Goto, EN Perencevich - Clinical infectious diseases, 2023 - academic.oup.com
Metformin, a biguanide, has become the preferred initial glucose-lowering agent for
managing type 2 diabetes over the last 2 decades. Its multimodal mechanisms of action (eg …
managing type 2 diabetes over the last 2 decades. Its multimodal mechanisms of action (eg …
Sodium-glucose co-transporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors on in-hospital mortality following pneumonia without heart failure: A retrospective …
Background Sodium-glucose co-transporter-2 inhibitors (SGLT2i) may contribute to better
clinical outcomes in adults with diabetes and pneumonia owing to their potential anti …
clinical outcomes in adults with diabetes and pneumonia owing to their potential anti …
Impact of metformin-use prior to pneumococcal vaccination on pneumococcal related disease and sepsis
SM Bandy - 2024 - repositories.lib.utexas.edu
Despite rapid diagnostic approaches, preventative medicine including vaccines (ie,
pneumococcal vaccines (PNVs)), and widely available antibiotics, pneumococcal disease …
pneumococcal vaccines (PNVs)), and widely available antibiotics, pneumococcal disease …
Genetically Proxied Glucose-Lowering Drug Target Perturbation and Risk of Pneumonia: A Mendelian Randomization Analysis
S Lin, H Xu, J Xia, F Xu - Available at SSRN 4987847 - papers.ssrn.com
Background: Type 2 diabetes mellitus (T2DM) and some glucose-lowering drugs are
associated with the incidence and mortality of pneumonia, but the causality remains unclear …
associated with the incidence and mortality of pneumonia, but the causality remains unclear …