Advanced situation with recombinant toxins: Diversity, production and application purposes

E Efremenko, A Aslanli, I Lyagin - International Journal of Molecular …, 2023 - mdpi.com
Today, the production and use of various samples of recombinant protein/polypeptide toxins
is known and is actively developing. This review presents state-of-the-art in research and …

Anti-inflammatory and analgesic effects of TRPV1 polypeptide modulator APHC3 in models of osteo-and rheumatoid arthritis

YA Logashina, YA Palikova, VA Palikov, VA Kazakov… - Marine drugs, 2021 - mdpi.com
Arthritis is a widespread inflammatory disease associated with progressive articular surface
degradation, ongoing pain, and hyperalgesia causing the development of functional …

Process scale-up criteria in production of recombinant proteins in E. coli: A systematic review

AHM Gameil, F Yusof, AS Azmi… - Chemical and Natural …, 2021 - journals.iium.edu.my
This systematic review provides an overview of the scale-up of recombinant protein
production. A systematic search was conducted using pre-established terms in four …

The study of TRPV1 channels of the central nervous system and their effect on anxiety in ICR mice

VM Pavlov, AY Fedotova, YA Andreev… - Doklady Biochemistry …, 2024 - Springer
The TRPV1 channel is actively involved in various neuronal processes and is found in
various structures of the nervous system, including peripheral and central neurons, sensory …

Optimized method for the recombinant production of a sea anemone's peptide

MN Tereshin, AM Komyakova, VN Stepanenko… - Mendeleev …, 2022 - Elsevier
The production of the analgesic peptide HCRG21 for medical use is restricted by a number
of limitations in the technology. The optimal biotechnological method scalable to industrial …

Novel strategy for expression of authentic and bioactive human basic fibroblast growth factor in Bacillus subtilis

X Hu, CYN Lai, T Sivakumar, H Wang, KL Ng… - Applied microbiology …, 2018 - Springer
Inteins, also known as “protein introns,” have been found to be present in many microbial
species and widely employed for the expression and purification of recombinant proteins in …

Recombinant Analogs of Sea Anemone Kunitz-Type Peptides Influence P2X7 Receptor Activity in Neuro-2a Cells

EA Pislyagin, ES Menchinskaya, IN Gladkikh… - Marine Drugs, 2023 - mdpi.com
Purinergic P2X7 receptors (P2X7) have now been proven to play an important role and
represent an important therapeutic target in many pathological conditions including …

[PDF][PDF] Методология биотехнологического получения рекомбинантных пептидов медицинского назначения

РС Есипов - Москва, 2019 - ibch.ru
Федеральное государственное бюджетное учреждении науки ИНСТИТУТ БИО Page 1
Федеральное государственное бюджетное учреждении науки ИНСТИТУТ …

Изучение стресс-протекторных свойств пептида APHC3 в тесте «Приподнятый крестообразный лабиринт» на мышах ICR

ВМ Павлов, АЮ Федотова - БИОМЕДИЦИНА, 2024 - journal.scbmt.ru
Аннотация TRPV1, играющий ключевую роль в передаче болевых сигналов, широко
распространён в различных тканях и клетках, включая ЦНС. Активация или подавление …

Изучение анксиолитических свойств антагониста TRPV1 рецепторов в тесте «Тёмная/светлая камера» на мышах ICR

АЮ Федотова, ВМ Павлов - БИОМЕДИЦИНА, 2024 - journal.scbmt.ru
Аннотация TRPV1, являющийся ключевым медиатором передачи ноцицептивных
сигналов, широко распространён в различных тканях и клетках, включая центральную …