Meisenheimer's missing! Anionic σ‐complexes, best known as Meisenheimer complexes,
have long been assumed to be intermediates in SNAr reactions. New evidence now …

Quaternary amino acids, in which the α-carbon that bears the amino and carboxyl groups
also carries two carbon substituents, have an important role as modifiers of peptide …

A method for the nucleophilic amination of methoxy arenes was established by using
sodium hydride (NaH) in the presence of lithium iodide (LiI). This method offers an efficient …

A simple protocol for hydrodebromination and‐deiodination of halo (hetero) arenes was
enabled by sodium hydride (NaH) in the presence of lithium iodide (LiI). Mechanistic studies …

The reaction rates of 4-X-2, 6-dinitrochlorobenzenes (X= NO2, CN, CF3) with Y-substituted
benzylamines (Y= p-OCH3, p-CH3, H, p-Cl) in MeOH-MeCN mixtures were measured by …

The kinetics and mechanism of the aromatic nucleophilic substitution reactions of 2, 6-bis (
trifluoromethanesulfonyl)-4-nitroanisole with para-X-substituted anilines (X= OH, OMe, Me …

When aromatic nucleophilic substitutions (ANS) with amines are carried out in solvents of
low permittivity, a third order in amine kinetic law is often determined. Initially considered an …

Temperature dependences of the relative reactivity of potassium aryloxides XC6H4O− K+
toward 4‐nitrophenyl (1), 3‐nitrophenyl (2), 4‐chlorophenyl (3), and phenyl (4) benzoates in …

A study was made of the influence of the substituent effects on the activation parameters
changes in the SN Ar reactions. It involved the analysis of both the free energy of activation∆ …

A nucleophilic substitution reaction of 4-chloro-7-nitrobenzofurazan (NBF-Cl) with anilines in
MeOH-MeCN mixtures was conducted at 25, 35, and 45 oC. Based on the higher βnuc …