Hydrogels for protein delivery

T Vermonden, R Censi, WE Hennink - Chemical reviews, 2012 - ACS Publications
Importantly, with the advent of hybridoma and recombinant DNA technologies, the limitations
associated with the extraction and purification of pharmaceutical proteins from animal …

An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing

DM Kirchmajer, R Gorkin Iii - Journal of Materials Chemistry B, 2015 - pubs.rsc.org
This review evaluates hydrogel-forming polymers that are suitable for soft tissue engineering
with a focus on materials that can be fabricated using additive manufacturing (3D-printing) …

Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles

C Wischke, SP Schwendeman - International Journal of pharmaceutics, 2008 - Elsevier
Injectable biodegradable and biocompatible copolymers of lactic and glycolic acid (PLGA)
are an important advanced delivery system for week-to-month controlled release of …

Biodegradable block copolymers for delivery of proteins and water-insoluble drugs

GM Zentner, R Rathi, C Shih, JC McRea… - Journal of controlled …, 2001 - Elsevier
Release of several drugs from new ABA-type biodegradable thermal gels, ReGel®,
including proteins and conventional molecules, are presented. These are biodegradable …

Thermogels: In situ gelling biomaterial

SS Liow, Q Dou, D Kai, AA Karim, K Zhang… - ACS Biomaterials …, 2016 - ACS Publications
In situ gel delivery systems are preferred over conventional systems due to sustained and
prolonged release action of therapeutic payload onto the targeted site. Thermogel, a form of …

In situ forming parenteral drug delivery systems: an overview

CB Packhaeuser, J Schnieders, CG Oster… - European Journal of …, 2004 - Elsevier
Biodegradable injectable in situ forming drug delivery systems represent an attractive
alternative to microspheres and implants as parenteral depot systems. Their importance will …

[PDF][PDF] In-situ gel: new trends in controlled and sustained drug delivery system

N HB, S Bakliwal, S Pawar - International Journal of PharmTech …, 2010 - academia.edu
Recently, controlled and sustained drug delivery has become the standard in modern
Pharmaceutical design and an intensive research have been undertaken in achieving much …

Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles

C Shih, G Zentner - US Patent 6,589,549, 2003 - Google Patents
A composition and method for releasing a bio-active agent or a drug within a biological
environment in a controlled manner is disclosed. The composition is a dual phase polymeric …

Injectable biodegradable temperature-responsive PLGA–PEG–PLGA copolymers: synthesis and effect of copolymer composition on the drug release from the …

M Qiao, D Chen, X Ma, Y Liu - International journal of pharmaceutics, 2005 - Elsevier
Injectable biodegradable temperature-responsive poly (dl-lactide-co-glycolide-b–ethylene
glycol-b-dl-lactide-co-glycolide)(PLGA–PEG–PLGA) triblock copolymers with dl …

Biodegradable thermogels

MH Park, MK Joo, BG Choi, B Jeong - Accounts of chemical …, 2012 - ACS Publications
All living creatures respond to external stimuli. Similarly, some polymers undergo
conformational changes in response to changes in temperature, pH, magnetic field …