Ten decadal advances in fungal biology leading towards human well-being

A Mapook, KD Hyde, K Hassan, BM Kemkuignou… - Fungal Diversity, 2022 - Springer
Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …

[HTML][HTML] CRISPR-Cas9 genome editing approaches in filamentous fungi and oomycetes

M Schuster, R Kahmann - Fungal Genetics and Biology, 2019 - Elsevier
Due to their biotechnological relevance as well as their importance as disease agents,
filamentous fungi and oomycetes have been prime candidates for genetic selection and in …

CRISPR/Cas9 genome editing technology in filamentous fungi: progress and perspective

R Song, Q Zhai, L Sun, E Huang, Y Zhang… - Applied microbiology …, 2019 - Springer
Filamentous fungi play an important role in human health and industrial/agricultural
production. With the increasing number of full genomes available for fungal species, the …

Exploring nano-enabled CRISPR-Cas-powered strategies for efficient diagnostics and treatment of infectious diseases

AK Dubey, V Kumar Gupta, M Kujawska… - Journal of Nanostructure …, 2022 - Springer
Biomedical researchers have subsequently been inspired the development of new
approaches for precisely changing an organism's genomic DNA in order to investigate …

Mucormycosis in 2023: An update on pathogenesis and management

A Alqarihi, DP Kontoyiannis, AS Ibrahim - Frontiers in Cellular and …, 2023 - frontiersin.org
Mucormycosis (MCR) is an emerging and frequently lethal fungal infection caused by the
Mucorales family, with Rhizopus, Mucor, and Lichtheimia, accounting for> 90% of all cases …

Applications of CRISPR/Cas9 in the synthesis of secondary metabolites in filamentous fungi

C Jiang, G Lv, Y Tu, X Cheng, Y Duan… - Frontiers in …, 2021 - frontiersin.org
Filamentous fungi possess the capacity to produce a wide array of secondary metabolites
with diverse biological activities and structures, such as lovastatin and swainsonine. With the …

CRISPR/Cas-based genome engineering in natural product discovery

Y Tong, T Weber, SY Lee - Natural product reports, 2019 - pubs.rsc.org
Covering: up to February, 2018 This review briefly introduces and summarizes current
knowledge about the Clustered Regularly Interspaced Short Palindromic Repeats …

Intercellular communication is required for trap formation in the nematode-trapping fungus Duddingtonia flagrans

L Youssar, V Wernet, N Hensel, X Yu… - PLoS …, 2019 - journals.plos.org
Nematode-trapping fungi (NTF) are a large and diverse group of fungi, which may switch
from a saprotrophic to a predatory lifestyle if nematodes are present. Different fungi have …

The CRISPR toolbox in medical mycology: State of the art and perspectives

F Morio, L Lombardi, G Butler - PLoS pathogens, 2020 - journals.plos.org
Fungal pathogens represent a major human threat affecting more than a billion people
worldwide. Invasive infections are on the rise, which is of considerable concern because …

Progress and challenges: development and implementation of CRISPR/Cas9 technology in filamentous fungi

Q Wang, JJ Coleman - Computational and structural biotechnology journal, 2019 - Elsevier
Widely distributed in various environmental niches, filamentous fungi play an important role
in industry, drug development, and plant/animal health. Manipulation of the genome and the …