Recent insights into nanotechnology in colorectal cancer

AAZ Dezfuli, M Abu-Elghait, SS Salem - Applied Biochemistry and …, 2024 - Springer
Colorectal cancer (CRC) is the third cancer among the known causes of cancer that impact
people. Although CRC drug options are imperfect, primary detection of CRC can play a key …

Triumph against cancer: invading colorectal cancer with nanotechnology

P Vinchhi, MM Patel - Expert Opinion on Drug Delivery, 2021 - Taylor & Francis
Introduction Recent statistics have reported colorectal cancer (CRC) as the second leading
cause of cancer-associated deaths in the world. Early diagnosis of CRC may help to reduce …

Chitosan-glucuronic acid conjugate coated mesoporous silica nanoparticles: A smart pH-responsive and receptor-targeted system for colorectal cancer therapy

R Narayan, S Gadag, SP Cheruku, AM Raichur… - Carbohydrate …, 2021 - Elsevier
Glycosylated pH-sensitive mesoporous silica nanoparticles (MSNs) of capecitabine (CAP)
were developed for targeting colorectal cancer. The MSNs possessed an average pore …

Encapsulation of red propolis in polymer nanoparticles for the destruction of pathogenic biofilms

IS de Mélo Silva, LM do Amorim Costa Gaspar… - Aaps Pharmscitech, 2020 - Springer
Microbial biofilms, structured communities of microorganisms, have been often associated to
the infection and bacterial multiresistance problem. Conventional treatment of infection …

Folic acid conjugated capecitabine capped green synthesized fluorescent carbon dots as a targeted nano-delivery system for colorectal cancer

S Paliwal, P Jana, S Singh, H Madhyastha… - Materials Today …, 2022 - Elsevier
Herein, we have developed folic acid conjugated capecitabine capped passivated carbon
dots (CAP-FA-CDPs) for colorectal cancer targeting. Carbon dots were synthesized via a …

Synthesis, physicochemical characterization, and in vitro evaluation of biodegradable PLGA nanoparticles entrapped to folic acid for targeted delivery of kaempferitrin

M Govindarasu, P Abirami, SS Alharthi… - Biotechnology and …, 2022 - Wiley Online Library
Polymeric nanoparticles are widely studied in the treatment of colorectal cancer.
Kaempferitrin‐loaded nontoxic and biodegradable poly (d, l‐lactic‐co‐glycolic acid)(PLGA) …

QbD enabled optimization of solvent shifting method for fabrication of PLGA-based nanoparticles for promising delivery of Capecitabine for antitumor activity

GK Jena, CN Patra, KC Panigrahi, J Sruti… - Drug Delivery and …, 2022 - Springer
The key objective of the current research was to fabricate and optimize Capecitabine (Cap)-
loaded [poly (lactic-co-glycolic acid)] PLGA-based nanoparticles (NPs) by enabling quality …

Advanced polymeric systems for colon drug delivery: from experimental models to market applications

R Crispino, E Lagreca, A Procopio, R D'Auria… - Soft Matter, 2025 - pubs.rsc.org
In recent years, nano and micro drug delivery systems targeting the colon have gained more
attention due to increasing interest in treating colon diseases such as colorectal cancer and …

CAPECITABINE IN THE MODERN MANAGEMENT OF COLON CANCER: CLINICAL OUTCOMES AND PERSPECTIVES

Y Garg, NR Sahoo, S Saxena, S Kumar, S Singh… - Journal of Drug Delivery …, 2024 - Elsevier
Abstract Oral prodrug of 5-fluorouracil (5-FU), capecitabine, has revolutionized the treatment
of colon cancer, providing high efficacy and convenient administration. This review …

Hydrophilic and hydrophobic polymeric benznidazole-loaded nanoparticles: Physicochemical properties and in vitro antitumor efficacy

AM dos Santos Silva, LB de Caland… - Journal of Drug Delivery …, 2019 - Elsevier
Benznidazole is a promising antitumor drug because it has the ability to induce the
production of intracellular reactive oxygen species. In this study, poly (d, l-lactide-co …