During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …

Background Evidence for the comparative teratogenic risk of antiepileptic drugs is
insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the …

The risks associated with use of antiepileptic drugs during pregnancy are a major concern
for all women with epilepsy with childbearing potential. These risks have to be balanced …

Abstract Background Antiseizure drugs (ASDs) are the primary therapy for epilepsy, with
more than 20 drugs introduced into clinical practice to date. These drugs are typically …

Summary Since 1989, 18 second-generation antiseizure medications have reached the
market, resulting in a greatly increased range of treatment options for patients and …

Objectives Compare the safety of antiepileptic drugs (AEDs) on neurodevelopment of
infants/children exposed in utero or during breast feeding. Design and setting Systematic …

The risk of adverse fetal effects differs in relation to the type of AED and for some AEDs also
the daily dose. Although for MCMs the risk is primarily associated with the first trimester of …

Objective This study was undertaken to examine the comparative safety of antiseizure
medication (ASM) monotherapy in pregnancy with respect to risk of major congenital …

Women with epilepsy (WWE) wishing for a child represent a highly relevant subgroup of
epilepsy patients. The treating epileptologist needs to delineate the epilepsy syndrome and …