[HTML][HTML] Intercellular transmission of pathogenic proteins in ALS: Exploring the pathogenic wave
FJ Arnold, AD Nguyen, RS Bedlack, CL Bennett… - Neurobiology of …, 2023 - Elsevier
In patients with amyotrophic lateral sclerosis (ALS), disease symptoms and pathology
typically spread in a predictable spatiotemporal pattern beginning at a focal site of onset and …
typically spread in a predictable spatiotemporal pattern beginning at a focal site of onset and …
Motor neurone disease
PJ Shaw - Handbook of neurological rehabilitation, 2005 - taylorfrancis.com
The precise cause (s) of the selective neurodegenerative process in motor neurone disease
(MND) remain unknown. For individuals afflicted with the disease, there is progressive …
(MND) remain unknown. For individuals afflicted with the disease, there is progressive …
CRISPR/Cas13d targeting suppresses repeat-associated non-AUG translation of C9orf72 hexanucleotide repeat RNA
A hexanucleotide GGGGCC repeat expansion in the non-coding region of the C9orf72 gene
is the most common genetic mutation identified in patients with amyotrophic lateral sclerosis …
is the most common genetic mutation identified in patients with amyotrophic lateral sclerosis …
Role of C9orf72 hexanucleotide repeat expansions in ALS/FTD pathogenesis
Y Geng, Q Cai - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are progressive
neurological disorders that share neurodegenerative pathways and features. The most …
neurological disorders that share neurodegenerative pathways and features. The most …
Dietary NMN supplementation enhances motor and NMJ function in ALS
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease that
causes the degeneration of motor neurons in the motor cortex and spinal cord. Patients with …
causes the degeneration of motor neurons in the motor cortex and spinal cord. Patients with …
RNP granules in ALS and neurodegeneration: From multifunctional membraneless organelles to therapeutic opportunities.
TA Shelkovnikova, GM Hautbergue - International Review of …, 2024 - europepmc.org
Amyotrophic lateral sclerosis (ALS) and related neurodegenerative diseases are
characterised by dysfunction of a host of RNA-binding proteins (RBPs) and a severely …
characterised by dysfunction of a host of RNA-binding proteins (RBPs) and a severely …
[PDF][PDF] Exploring cellular toxicity mechanisms and immunotherapeutic potential of TDP-43 in ALS/FTD
H Riemenschneider - 2024 - edoc.ub.uni-muenchen.de
CFTR CF transmembrane conductance regulator CHMP2B Charged multivesicular body
protein 2B CK1δ/ε or 2 Casein kinase 1δ/ε or 2 CMA Chaperone-mediated autophagy CNS …
protein 2B CK1δ/ε or 2 Casein kinase 1δ/ε or 2 CMA Chaperone-mediated autophagy CNS …
[PDF][PDF] Aktive und passive anti-GA Immuntherapie für C9orf72 ALS/FTD im Mausmodell
N Mareljic - 2023 - edoc.ub.uni-muenchen.de
Zusammenfassung Frontotemporale Demenz (FTD) und Amyotrophe lateral Sklerose (ALS)
sind neurodegenerative Erkrankungen, die sowohl klinisch als auch pathologisch und …
sind neurodegenerative Erkrankungen, die sowohl klinisch als auch pathologisch und …
The C9orf72 dipeptide repeat protein poly-glycine-alanine sequesters nucleoporins and disrupts nuclear membranes
K Richter - 2022 - theses.hal.science
In patients with familial amyotrophic lateral sclerosis (ALS) who carry a mutation in the
C9ORF72 gene, dipeptide-repeat proteins accumulate in nervous system tissue. Of these …
C9ORF72 gene, dipeptide-repeat proteins accumulate in nervous system tissue. Of these …
[引用][C] Aktive und passive anti-GA Immuntherapie für C9orf72 ALS/FTD im Mausmodell
N Mareljic - Dissertation, München, Ludwig …