Development of different pretreatments and related technologies for efficient biomass conversion of lignocellulose

M Zhou, X Tian - International Journal of Biological Macromolecules, 2022 - Elsevier
Lignocellulose, a kind of biological resource widely existing in nature, which can be
transformed into value-added biochemical products through saccharification, fermentation or …

Particle size reduction techniques of pharmaceutical compounds for the enhancement of their dissolution rate and bioavailability

R Kumar, AK Thakur, P Chaudhari… - Journal of Pharmaceutical …, 2022 - Springer
In pharmaceutical research and development, various new chemical entities (NCE) are
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …

Supercritical fluids for pharmaceutical particle engineering: Methods, basic fundamentals and modelling

A Tabernero, EMM del Valle, MA Galán - Chemical Engineering and …, 2012 - Elsevier
The interest of the use of supercritical fluids, especially supercritical CO2, for particle
engineering over the last years has received attention from the pharmaceutical industry …

Mechanisms controlling supercritical antisolvent precipitate morphology

E Reverchon, I De Marco - Chemical Engineering Journal, 2011 - Elsevier
Supercritical antisolvent precipitation (SAS) has been successfully used to micronize several
kinds of materials. A great variety of morphologies, such as nanoparticles with mean …

Interactions of phase equilibria, jet fluid dynamics and mass transfer during supercritical antisolvent micronization

E Reverchon, E Torino, S Dowy, A Braeuer… - Chemical Engineering …, 2010 - Elsevier
Supercritical antisolvent (SAS) precipitation has been successfully used in the micronization
of several compounds. Nevertheless, the role of high-pressure vapor–liquid equilibria, jet …

Supercritical antisolvent coprecipitation mechanisms

V Prosapio, I De Marco, E Reverchon - The Journal of Supercritical Fluids, 2018 - Elsevier
Supercritical antisolvent precipitation (SAS) has been successfully used to produce
microparticles and nanoparticles of controlled size and distribution either as a single …

Particle preparation of pharmaceutical compounds using supercritical antisolvent process: current status and future perspectives

R Kumar, AK Thakur, G Kali, KC Pitchaiah… - Drug Delivery and …, 2023 - Springer
The low aqueous solubility and subsequently slow dissolution rate, as well as the poor
bioavailability of several active pharmaceutical ingredients (APIs), are major challenges in …

Use of compressed gas precipitation to enhance the dissolution behavior of a poorly water-soluble drug: generation of drug microparticles and drug–polymer solid …

G Muhrer, U Meier, F Fusaro, S Albano… - International journal of …, 2006 - Elsevier
The classical anticonvulsant drug phenytoin (5, 5-diphenyl hydantoin, C15H12N2O2) has
been used as a model compound to investigate the possibility of enhancing the dissolution …

Supercritical and transcritical turbulent injection processes: Consistency of numerical modeling

F Ries, A Sadiki - Atomization and Sprays, 2021 - dl.begellhouse.com
The present paper reviews recent achievements in numerical modeling of super-and
transcritical injection processes during the last 20 years. First, it provides an overview of …

Laminar jet dispersion and jet atomization in pressurized carbon dioxide

E Badens, O Boutin, G Charbit - The Journal of supercritical fluids, 2005 - Elsevier
Laminar jet dispersion and more particularly jet atomization of water, methylene chloride
and ethyl alcohol into pressurized carbon dioxide are investigated under experimental …