Given the highly increased incidence of human diseases, a better understanding of the
related mechanisms regarding endogenous metabolism is urgently needed. Mass …

Metabolomics is a young field of knowledge that arises linked to other omics such as
genomics, transcriptomics, and proteomics. This discipline seeks to understand the …

High-performance metabolic analysis is emerging in the diagnosis and prognosis of breast
cancer (BrCa). Still, advanced tools are in demand to deliver the application potentials of …

Alzheimer's disease (AD) risk gene ApoE4 perturbs brain lipid homeostasis and energy
transduction. However, the cell-type-specific mechanism of ApoE4 in modulating brain lipid …

Breast cancer (BC) is a common cause of morbidity and mortality, particularly in women.
Moreover, the discovery of diagnostic biomarkers for early BC remains a challenging task …

Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …

Dendritic cells (DCs) rely on glycolysis for their energy needs to induce pro-inflammatory
antigen-specific immune responses. Therefore, inhibiting DC glycolysis, while presenting …

Targeted mass spectrometry (MS) is an important measurement approach in metabolomics
with strong analytical performance, given its specificity, sensitivity, and quantitative capacity …

Breast cancer (BC) is a heterogeneous malignancy that is responsible for a great portion of
female cancer cases and cancer-related deaths in the United States. In comparison to other …

Lipids are essential components of cell structure and play important roles in signal
transduction between cells and body metabolism. With the continuous development and …