Pathogenicity and virulence of the liver flukes Fasciola hepatica and Fasciola Gigantica that cause the zoonosis Fasciolosis
R Lalor, K Cwiklinski, NED Calvani, A Dorey, S Hamon… - Virulence, 2021 - Taylor & Francis
Fasciolosis caused by the liver flukes Fasciola hepatica and Fasciola gigantica is one of the
most important neglected parasitic diseases of humans and animals. The ability of the …
most important neglected parasitic diseases of humans and animals. The ability of the …
Fascioliasis and fasciolopsiasis: Current knowledge and future trends
M Siles-Lucas, D Becerro-Recio, J Serrat… - Research in veterinary …, 2021 - Elsevier
Food-borne zoonotic trematodiases are classified as neglected diseases by the World
Health Organization. Among them, fascioliasis is caused worldwide by Fasciola hepatica …
Health Organization. Among them, fascioliasis is caused worldwide by Fasciola hepatica …
Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the …
K Cwiklinski, MW Robinson, S Donnelly, JP Dalton - BMC genomics, 2021 - Springer
Background The major pathogenesis associated with Fasciola hepatica infection results
from the extensive tissue damage caused by the tunnelling and feeding activity of immature …
from the extensive tissue damage caused by the tunnelling and feeding activity of immature …
Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the …
Background MiRNAs are small non-coding RNAs that post-transcriptionally regulate gene
expression in organisms ranging from viruses to mammals. There is great relevance in …
expression in organisms ranging from viruses to mammals. There is great relevance in …
Omics tools enabling vaccine discovery against fasciolosis
K Cwiklinski, JP Dalton - Trends in Parasitology, 2022 - cell.com
In the past decade significant advances in our understanding of liver fluke biology have
been made through in-depth interrogation and analysis of evolving Fasciola hepatica and …
been made through in-depth interrogation and analysis of evolving Fasciola hepatica and …
microRNAs: critical players during helminth infections
M Rojas-Pirela, D Andrade-Alviárez, W Quiñones… - Microorganisms, 2022 - mdpi.com
microRNAs (miRNAs) are a group of small non-coding RNAs that regulate gene expression
post-transcriptionally through their interaction with the 3′ untranslated regions (3′ UTR) of …
post-transcriptionally through their interaction with the 3′ untranslated regions (3′ UTR) of …
Towards the comprehension of fasciolosis (re-) emergence: an integrative overview
A Alba, AA Vazquez, S Hurtrez-Boussès - Parasitology, 2021 - cambridge.org
The increasing distribution and prevalence of fasciolosis in both human and livestock are
concerning. Here, we examine the various types of factors influencing fasciolosis …
concerning. Here, we examine the various types of factors influencing fasciolosis …
An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica
D Smith, K Cwiklinski, H Jewhurst, IG Tikhonova… - Scientific Reports, 2020 - nature.com
Fasciola hepatica is a global parasite of humans and their livestock. Regulation of parasite-
secreted cathepsin L-like cysteine proteases associated with virulence is important to fine …
secreted cathepsin L-like cysteine proteases associated with virulence is important to fine …
High-quality reference genome of Fasciola gigantica: Insights into the genomic signatures of transposon-mediated evolution and specific parasitic adaption in tropical …
X Luo, K Cui, Z Wang, Z Li, Z Wu… - PLoS Neglected …, 2021 - journals.plos.org
Fasciola gigantica and Fasciola hepatica are causative pathogens of fascioliasis, with the
widest latitudinal, longitudinal, and altitudinal distribution; however, among parasites, they …
widest latitudinal, longitudinal, and altitudinal distribution; however, among parasites, they …
The discovery of Fasciola hepatica and its life cycle.
SJ Andrews, K Cwiklinski, JP Dalton - Fasciolosis, 2021 - cabidigitallibrary.org
1 The Discovery of Fasciola hepatica and its Life Cycle Page 1 © CAB International 2022.
Fasciolosis, 2nd Edition (ed. JP Dalton) DOI: 10.1079/9781789246162.0001 1 1.1 …
Fasciolosis, 2nd Edition (ed. JP Dalton) DOI: 10.1079/9781789246162.0001 1 1.1 …