Update on tuberculosis biomarkers: from correlates of risk, to correlates of active disease and of cure from disease
D Goletti, MR Lee, JY Wang, N Walter… - …, 2018 - Wiley Online Library
Tuberculosis (TB) remains a devastating disease, yet despite its enormous toll on global
health, tools to control TB are insufficient and often outdated. TB Biomarkers (TB‐BM) would …
health, tools to control TB are insufficient and often outdated. TB Biomarkers (TB‐BM) would …
Human immunology of tuberculosis
Immunology is a central theme when it comes to tuberculosis (TB). The outcome of human
infection with Mycobacterium tuberculosis is dependent on the ability of the immune …
infection with Mycobacterium tuberculosis is dependent on the ability of the immune …
Quantitative and qualitative profiles of circulating monocytes may help identifying tuberculosis infection and disease stages
Tuberculosis (TB) is one of the most important cause of morbidity and death among
infectious diseases, and continuous efforts are needed to improve diagnostic tools and …
infectious diseases, and continuous efforts are needed to improve diagnostic tools and …
TB vaccine development and the End TB Strategy: importance and current status
HA Fletcher, L Schrager - Transactions of the Royal Society of …, 2016 - academic.oup.com
TB is now the leading, global cause of death due to a single infectious microbe. To achieve
the End TB vision of reducing TB by 90% by 2035 we will need new interventions. The …
the End TB vision of reducing TB by 90% by 2035 we will need new interventions. The …
[HTML][HTML] Accuracy of monocyte to lymphocyte ratio for tuberculosis diagnosis and its role in monitoring anti-tuberculosis treatment: Systematic review and meta …
Background: High monocyte to lymphocyte ratio (MLR) values may be associated with the
risk of active tuberculosis (TB) infection in adults, infants, and postpartum women with HIV …
risk of active tuberculosis (TB) infection in adults, infants, and postpartum women with HIV …
Distinct transcriptional and anti-mycobacterial profiles of peripheral blood monocytes dependent on the ratio of monocytes: lymphocytes
The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with
tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We …
tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We …
Bridging the gaps to overcome major hurdles in the development of next-generation tuberculosis vaccines
H Kim, HG Choi, SJ Shin - Frontiers in Immunology, 2023 - frontiersin.org
Although tuberculosis (TB) remains one of the leading causes of death from an infectious
disease worldwide, the development of vaccines more effective than bacille Calmette …
disease worldwide, the development of vaccines more effective than bacille Calmette …
Ratios from full blood count as markers for TB diagnosis, treatment, prognosis: a systematic review
N Fritschi, N Vaezipour, M Buettcher… - … of Tuberculosis and …, 2023 - ingentaconnect.com
BACKGROUND: The monocyte-to-lymphocyte (MLR) and neutrophil-to-lymphocyte (NLR)
ratio are calculated from routine full blood counts. The aim of this study was to systematically …
ratio are calculated from routine full blood counts. The aim of this study was to systematically …
Monocyte-to-lymphocyte ratio is associated with tuberculosis disease and declines with anti-TB treatment in HIV-infected children
Background: The blood monocyte-to-lymphocyte ratio (MLR) is associated with active
tuberculosis (TB) in adults but has not been evaluated as a TB diagnostic biomarker in HIV …
tuberculosis (TB) in adults but has not been evaluated as a TB diagnostic biomarker in HIV …
The monocyte-to-lymphocyte ratio: Sex-specific differences in the tuberculosis disease spectrum, diagnostic indices and defining normal ranges
TS Buttle, CY Hummerstone, T Billahalli, RJB Ward… - PloS one, 2021 - journals.plos.org
Background The monocyte-to-lymphocyte ratio (MLR) has been advocated as a biomarker
in tuberculosis. Our objective was to evaluate its clinical value and associations. Methods …
in tuberculosis. Our objective was to evaluate its clinical value and associations. Methods …