[HTML][HTML] Bacterial capsules: Occurrence, mechanism, and function
S Gao, W Jin, Y Quan, Y Li, Y Shen, S Yuan… - npj Biofilms and …, 2024 - nature.com
In environments characterized by extended multi-stress conditions, pathogens develop a
variety of immune escape mechanisms to enhance their ability to infect the host. The …
variety of immune escape mechanisms to enhance their ability to infect the host. The …
Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections
During severe infections, Staphylococcus aureus moves from its colonising sites to blood
and tissues and is exposed to new selective pressures, thus, potentially driving adaptive …
and tissues and is exposed to new selective pressures, thus, potentially driving adaptive …
[HTML][HTML] On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis
The opportunistic pathogen Staphylococcus aureus frequently colonizes the inflamed skin of
people with atopic dermatitis (AD) and worsens disease severity by promoting skin damage …
people with atopic dermatitis (AD) and worsens disease severity by promoting skin damage …
Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins
A Siegmund, MA Afzal, F Tetzlaff, D Keinhörster… - Virulence, 2021 - Taylor & Francis
ABSTRACT A large proportion of clinical S. aureus isolates that carry an inactive Agr system
are associated with persistent infection that is difficult to treat. Once S. aureus is inside the …
are associated with persistent infection that is difficult to treat. Once S. aureus is inside the …
The Capsular Polysaccharide Obstructs Wall Teichoic Acid Functions in Staphylococcus aureus
E Lehmann, R van Dalen, L Gritsch… - The Journal of …, 2024 - academic.oup.com
Background The cell envelope of Staphylococcus aureus contains two major secondary cell
wall glycopolymers: capsular polysaccharide (CP) and wall teichoic acid (WTA). Both the CP …
wall glycopolymers: capsular polysaccharide (CP) and wall teichoic acid (WTA). Both the CP …
Bacterial adhesion, virulence, and biofilm formation
AS Pugazhendhi, F Wei, M Hughes… - Musculoskeletal Infection, 2022 - Springer
The adhesion of bacteria to implanted biomaterial and human tissue surfaces is the first and
essential step in the pathogenesis of infection. Adhesion is followed by the formation of a …
essential step in the pathogenesis of infection. Adhesion is followed by the formation of a …
[PDF][PDF] On-person adaptive evolution of Staphylococcus aureus during atopic dermatitis increases disease severity
Bacteria acquire adaptive mutations during infections and within healthy microbiomes 1-4,
but the potential of bacterial mutations to impact disease is not well understood. The …
but the potential of bacterial mutations to impact disease is not well understood. The …