Brain-derived neurotrophic factor rs6265 (Val66Met) single nucleotide polymorphism as a master modifier of human pathophysiology

B Hill, N Sims, A Heck, M Negron, C Lusk… - Neural Regeneration …, 2023 - journals.lww.com
Brain-derived neurotrophic factor is the most prevalent member of the nerve growth factor
family. Since its discovery in 1978, this enigmatic molecule has spawned more than 27,000 …

Role of BDNF in neuroplasticity associated with alcohol dependence

DI Peregud, VY Baronets, NN Terebilina… - Biochemistry …, 2023 - Springer
Chronic alcohol consumption is characterized by disturbances of neuroplasticity. Brain-
derived neurotrophic factor (BDNF) is believed to be critically involved in this process. Here …

Early postnatal ethanol exposure in mice induces sex-dependent memory impairment and reduction of hippocampal NMDA-R2B expression in adulthood

A Ieraci, DG Herrera - Neuroscience, 2020 - Elsevier
Drinking alcohol during pregnancy is particularly detrimental for the developing brain and
may cause a broad spectrum of cognitive and behavioral impairments, collectively known as …

The interaction of BDNF with estrogen in the development of hypertension and obesity, particularly during menopause

Z Zhang, Z He, J Pan, M Yuan, Y Lang, X Wei… - Frontiers in …, 2024 - frontiersin.org
The expression of BDNF in both neuronal and non-neuronal cells is influenced by various
stimuli, including prenatal developmental factors and postnatal conditions such as …

MINI-REVIEW ON THE IMPLICATIONS OF GENE POLYMORPHISM IN THE METABOLISM OF XENOBIOTICS.

AC Luca, A Ciobica, W Bild, AS Curpan… - Farmacia, 2022 - search.ebscohost.com
One of the most common medical issues in children and adults is accidental poisonings
ranging from medicines to toxic substances such as alcohol and toluene and even metals …

The brain basis of comorbidity in neurodevelopmental disorders

MK Licari, A Finlay-Jones, JE Reynolds… - Current Developmental …, 2019 - Springer
Abstract Purpose of Review Research examining brain development in neurodevelopmental
disorders has largely comprised small-scale studies on individual disorders. Findings have …

Enhancement of parvalbumin interneuron-mediated neurotransmission in the retrosplenial cortex of adolescent mice following third trimester-equivalent ethanol …

CW Bird, GJ Chavez, MJ Barber, CF Valenzuela - Scientific Reports, 2021 - nature.com
Prenatal ethanol exposure causes a variety of cognitive deficits that have a persistent impact
on quality of life, some of which may be explained by ethanol-induced alterations in …

Associations between brain‐derived neurotrophic factor and cognitive impairment in panic disorder

W Wang, Y Liu, S Luo, X Guo, X Luo… - Brain and …, 2020 - Wiley Online Library
Introduction Our study was designed to examine the relationship between Brain‐Derived
Neurotrophic Factor (BDNF) genotypes (rs6265, Val66Met), BDNF plasma levels, and …

Prefrontal Cortical Projection Neurons: Involvement in Shaping Different Types of Behaviors, BDNF Expression and Transport

US Drozd, YA Frik, AV Smagin… - Journal of Evolutionary …, 2024 - Springer
The prefrontal cortex (PFC) plays a key role in cognitive plasticity and is involved in various
processes of higher nervous activity. At the same time, studying the processes underlying …

[HTML][HTML] Association of plasma pro-brain-derived neurotrophic factor (proBDNF)/mature brain-derived neurotrophic factor (mBDNF) levels with BDNF gene Val66Met …

M Mo, X Fu, X Zhang, S Zhang, H Zhang… - … medical journal of …, 2021 - ncbi.nlm.nih.gov
Background In a previous study, we reported that pro-brain-derived neurotrophic factor
(proBDNF) was involved in the pathology of alcohol dependence, and the single-nucleotide …