Glycine is a major amino acid in mammals and other animals. It is synthesized from serine,
threonine, choline, and hydroxyproline via inter-organ metabolism involving primarily the …

L-serine is a nonessential amino acid in eukaryotic cells, used for protein synthesis and in
producing phosphoglycerides, glycerides, sphingolipids, phosphatidylserine, and …

Background-Enzymes that depend on vitamin B6 (and in particular on its metabolically
active form, pyridoxal 5'-phosphate, PLP) are of great relevance to biology and medicine, as …

Organisms from all kingdoms of life synthesize L‐serine (L‐Ser) from 3‐phosphoglycerate
through the phosphorylated pathway, a three‐step diversion of glycolysis. Phosphoserine …

The present review focuses on a subfamily of pyridoxal phosphate (PLP)-dependent
enzymes, belonging to the broader fold-type I structural group and whose archetypes can be …

Phosphonates—compounds containing a direct C–P bond—represent an important source
of phosphorus in some environments. The most common natural phosphonate is 2 …

Abstract The Primary Hyperoxaluria's (PH) are rare autosomal recessive disorders
characterized by elevated oxalate production. PH patients suffer recurrent calcium oxalate …

Phosphonates represent an important source of bioavailable phosphorus in certain
environments. Accordingly, many microorganisms (particularly marine bacteria) possess …

Background Primary hyperoxaluria type 1 (PH1) is an inborn error of glyoxylate metabolism,
characterized by increased endogenous oxalate production. The metabolic pathways …

Transaminases play key roles in central metabolism, transferring the amino group from a
donor substrate to an acceptor. These enzymes can often act, with low efficiency, on …