Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination

P Irrgang, J Gerling, K Kocher, D Lapuente… - Science …, 2022 - science.org
RNA vaccines are efficient preventive measures to combat the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic. High levels of neutralizing SARS-CoV-2 …

Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection

FJ Ryan, CM Hope, MG Masavuli, MA Lynn… - BMC medicine, 2022 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …

Comparison of seroconversion in children and adults with mild COVID-19

ZQ Toh, J Anderson, N Mazarakis, M Neeland… - JAMA network …, 2022 - jamanetwork.com
Importance The immune response in children with SARS-CoV-2 infection is not well
understood. Objective To compare seroconversion in nonhospitalized children and adults …

[HTML][HTML] Non-neutralizing functions in anti-SARS-CoV-2 IgG antibodies

S Reinig, SR Shih - Biomedical Journal, 2024 - Elsevier
Most individuals infected with or vaccinated against COVID-19 develop antigenic
neutralizing immunoglobulin G (IgG) antibodies against the SARS-CoV-2 spike protein …

[HTML][HTML] SARS-CoV-2 antibodies mediate complement and cellular driven inflammation

I Jarlhelt, SK Nielsen, CXH Jahn, CB Hansen… - Frontiers in …, 2021 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to constitute a serious …

Inactivated COVID-19 vaccines: potential concerns of antibody-dependent enhancement and original antigenic sin

AKC Kan, PH Li - Immunology Letters, 2023 - Elsevier
Inactivated vaccine is one of the platforms employed in COVID-19 vaccines. Inactivated
vaccines have been associated with concerns of antibody-dependent enhancement (ADE) …

Neutralizing activity and SARS-CoV-2 vaccine mRNA persistence in serum and breastmilk after BNT162b2 vaccination in lactating women

KT Yeo, WN Chia, CW Tan, C Ong, JG Yeo… - Frontiers in …, 2022 - frontiersin.org
Background There is limited information on the functional neutralizing capabilities of
breastmilk SARS-CoV-2-specific antibodies and the potential adulteration of breastmilk with …

Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors

M Steenhuis, G van Mierlo, NIL Derksen… - Clinical & …, 2021 - Wiley Online Library
Objectives Characterisation of the human antibody response to SARS‐CoV‐2 infection is
vital for serosurveillance purposes and for treatment options such as transfusion with …

IgG3 and IgM identified as key to SARS-CoV-2 neutralization in convalescent plasma pools

C Kober, S Manni, S Wolff, T Barnes, S Mukherjee… - PLoS …, 2022 - journals.plos.org
Analysis of convalescent plasma derived from individuals has shown that IgG3 has the most
important role in binding to SARS-CoV-2 antigens; however, this has not yet been confirmed …

Does SARS-CoV-2 induce IgG4 synthesis to evade the immune system?

A Rubio-Casillas, EM Redwan, VN Uversky - Biomolecules, 2023 - mdpi.com
SARS-CoV-2, the virus that causes the COVID-19 disease, has been shown to cause
immune suppression in certain individuals. This can manifest as a reduced ability of the …