Asthma is one of the most common diseases in the world, resulting in a substantial burden of
disease. Although rates of deaths due to asthma worldwide have reduced greatly over the …

Gender differences in asthma incidence, prevalence and severity have been reported
worldwide. After puberty, asthma becomes more prevalent and severe in women, and is …

Interest in the contribution of changes in lung development during early life to subsequent
respiratory morbidity is increasing. Most evidence of an association between adverse …

Sex differences in the biology of different organ systems and the influence of sex hormones
in modulating health and disease are increasingly relevant in clinical and research areas …

Asthma that starts in adulthood differs from childhood-onset asthma in that it is often non-
atopic, more severe and associated with a faster decline in lung function. Understanding of …

Background Although women with severe non-allergic asthma may represent a substantial
proportion of adults with asthma in clinical practice, gender differences in the incidence of …

Abstract Purpose of Review Allergen is an umbrella term for irritants of diverse origin. Along
with other offenders such as pathogens, mutagens, xenobiotics, and pollutants, allergens …

Background The “asthma epidemic” is on the rise, with the Center for Disease Control (CDC)
epidemiological studies reporting a 3.0% asthma prevalence in the United States in 1970 …

The role of testosterone in the pathophysiology of inflammation is of critical clinical
importance; however, no universal mechanism (s) has been advanced to explain the …

BACKGROUND: During puberty, a gender shift in asthma prevalence occurs, with a
preponderance of boys before puberty. The mechanisms underlying this gender shift are …