LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer

A Bhan, SS Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Non-coding RNAs (ncRNAs) are emerging classes of regulatory RNA that play key roles in
various cellular and physiological processes such as in gene regulation, chromatin …

MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications

AM Strubberg, BB Madison - Disease models & …, 2017 - journals.biologists.com
MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …

[HTML][HTML] Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer

H Xie, X Ren, S Xin, X Lan, G Lu, Y Lin, S Yang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs), a large class of RNAs, have recently shown huge capabilities as
gene regulators in mammals. Some of them bind with microRNAs (miRNAs) and act as …

NanoStringDiff: a novel statistical method for differential expression analysis based on NanoString nCounter data

H Wang, C Horbinski, H Wu, Y Liu, S Sheng… - Nucleic acids …, 2016 - academic.oup.com
The advanced medium-throughput NanoString nCounter technology has been increasingly
used for mRNA or miRNA differential expression (DE) studies due to its advantages …

[HTML][HTML] Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm

M Roshani, D Molavizadeh, S Sadeghi, A Jafari… - Biomedicine & …, 2023 - Elsevier
Gastrointestinal (GI) carcinomas are a group of cancers affecting the GI tract and digestive
organs, such as the gastric, liver, bile ducts, pancreas, small intestine, esophagus, colon …

The PI3K/AKT signaling pathway: associations of miRNAs with dysregulated gene expression in colorectal cancer

ML Slattery, LE Mullany, LC Sakoda… - Molecular …, 2018 - Wiley Online Library
The PI3K/AKT‐signaling pathway is one of the most frequently activated signal‐transduction
pathways in cancer. We examined how dysregulated gene expression is associated with …

MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9

P Vychytilova-Faltejskova, J Merhautova… - Oncogenesis, 2017 - nature.com
Growing evidence suggests that microRNAs are involved in the development and
progression of colorectal cancer (CRC). In the present study, deregulation and functioning of …

The co‐regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer

ML Slattery, JS Herrick, LE Mullany… - Genes …, 2017 - Wiley Online Library
Tumor suppressor genes (TSGs) and oncogenes (OG) are involved in carcinogenesis.
MiRNAs also contribute to cellular pathways leading to cancer. We use data from 217 …

The NF-κB signalling pathway in colorectal cancer: associations between dysregulated gene and miRNA expression

ML Slattery, LE Mullany, L Sakoda… - Journal of cancer …, 2018 - Springer
Background The nuclear factor-kappa B (NF-κB) signalling pathway is a regulator of immune
response and inflammation that has been implicated in the carcinogenic process. We …

CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p

S Wang, X Xue, R Wang, X Li, Q Li… - Cancer management …, 2018 - Taylor & Francis
Background Accumulating evidence suggests that circular RNAs (circRNAs) play critical
roles in carcinomas. However, the contributions of circRNAs to breast cancer remain …