Central regulation of stress-evoked peripheral immune responses

KL Chan, WC Poller, FK Swirski… - Nature Reviews …, 2023 - nature.com
Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

Neurobiology and systems biology of stress resilience

R Kalisch, SJ Russo, MB Müller - Physiological Reviews, 2024 - journals.physiology.org
Stress resilience is the phenomenon that some people maintain their mental health despite
exposure to adversity or show only temporary impairments followed by quick recovery …

[HTML][HTML] Circulating myeloid-derived MMP8 in stress susceptibility and depression

F Cathomas, HY Lin, KL Chan, L Li, LF Parise… - Nature, 2024 - nature.com
Psychosocial stress has profound effects on the body, including the immune system and the
brain,. Although a large number of pre-clinical and clinical studies have linked peripheral …

Sex differences in stress response: classical mechanisms and beyond

GE Hodes, D Bangasser, I Sotiropoulos… - Current …, 2024 - benthamdirect.com
Neuropsychiatric disorders, which are associated with stress hormone dysregulation, occur
at different rates in men and women. Moreover, nowadays, preclinical and clinical evidence …

Neuroimmune mechanisms of opioid use disorder and recovery: Translatability to human studies, and future research directions

ER Butelman, RZ Goldstein, CA Nwaneshiudu… - Neuroscience, 2023 - Elsevier
Opioid use disorder (OUD) is a major current cause of morbidity and mortality. Long-term
exposure to short-acting opioids (MOP-r agonists such as heroin or fentanyl) results in …

[HTML][HTML] Transcriptome alterations caused by social defeat stress of various durations in mice and its relevance to depression and posttraumatic stress disorder in …

VV Reshetnikov, PE Kisaretova, NP Bondar - International journal of …, 2022 - mdpi.com
The research on molecular causes of stress-associated psychopathologies is becoming
highly important because the number of people with depression, generalized anxiety …

[HTML][HTML] Genomic modules and intramodular network concordance in susceptible and resilient male mice across models of stress

SG Caradonna, TY Zhang, N O'Toole… - …, 2022 - nature.com
The multifactorial etiology of stress-related disorders necessitates a constant interrogation of
the molecular convergences in preclinical models of stress that use disparate paradigms as …

[HTML][HTML] Toward understanding the sex differences in the biological mechanism of social stress in mouse models

A Takahashi - Frontiers in psychiatry, 2021 - frontiersin.org
Significant sex differences in terms of prevalence, symptomatic profiles, severity, and
comorbidities of psychiatric disorders are quite common. Women have been shown to be …

[HTML][HTML] Spinal microglial activation promotes perioperative social defeat stress-induced prolonged postoperative pain in a sex-dependent manner

W Wang, WZ Liu, ZL Wang, DX Duan, XY Wang… - Brain, Behavior, and …, 2022 - Elsevier
Prolonged postsurgical pain, which is associated with multiple risk factors in the
perioperative stage, is a common medical and social problem worldwide. Suitable animal …

Chemokine receptor 5 signaling in PFC mediates stress susceptibility in female mice

HY Lin, F Cathomas, L Li, RD Cuttoli, C Guevara… - bioRxiv, 2023 - biorxiv.org
Chronic stress induces changes in the periphery and the central nervous system (CNS) that
contribute to neuropathology and behavioral abnormalities associated with psychiatric …