Rutin as a potent antioxidant: Implications for neurodegenerative disorders

AB Enogieru, W Haylett, DC Hiss… - Oxidative medicine …, 2018 - Wiley Online Library
A wide range of neurodegenerative diseases (NDs), including Alzheimer's disease,
Parkinson's disease, Huntington's disease, and prion diseases, share common mechanisms …

Flavonoids as therapeutic agents in Alzheimer's and Parkinson's diseases: a systematic review of preclinical evidences

RB de Andrade Teles, TC Diniz… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's and Parkinson's diseases are considered the most common neurodegenerative
disorders, representing a major focus of neuroscience research to understanding the …

[HTML][HTML] Antioxidant Properties of Pulp, Peel and Seeds of Phlegrean Mandarin (Citrus reticulata Blanco) at Different Stages of Fruit Ripening

G Costanzo, E Vitale, MR Iesce, D Naviglio… - Antioxidants, 2022 - mdpi.com
In this work, we assess the potential of waste products of Phlegrean mandarin (Citrus
reticulata Blanco), namely seeds and peel, to be reutilized as a source of bioactive …

[HTML][HTML] Potential therapeutic use of plant flavonoids in AD and PD

S Meng-Zhen, L Ju, Z Lan-Chun, D Cai-Feng… - Heliyon, 2022 - cell.com
Background Millions of people suffer from Alzheimer's disease (AD) and Parkinson's
disease (PD) worldwide. Due to their complex pathology, no effective pharmacological …

[HTML][HTML] Anti-inflammatory effects of flavonoids in common neurological disorders associated with aging

H Martínez-Coria, I Arrieta-Cruz… - International journal of …, 2023 - mdpi.com
Aging reduces homeostasis and contributes to increasing the risk of brain diseases and
death. Some of the principal characteristics are chronic and low-grade inflammation, a …

Rutin as neuroprotective agent: From bench to bedside

B Budzynska, C Faggio, M Kruk-Slomka… - Current medicinal …, 2019 - ingentaconnect.com
Flavonoids are major dietary constituents of plant-based food found ubiquitously in plant
kingdom where they are usually present in substantial amounts. Rutin is a flavonol-type …

Role of flavonoids in neurodegenerative diseases: limitations and future perspectives

G Maan, B Sikdar, A Kumar, R Shukla… - Current Topics in …, 2020 - ingentaconnect.com
Background: Flavonoids, a group of natural dietary polyphenols, are known for their
beneficial effects on human health. By virtue of their various pharmacological effects, like …

Normalization of HPA axis, cholinergic neurotransmission, and inhibiting brain oxidative and inflammatory dynamics are associated with the adaptogenic-like effect of …

JOT Emudainohwo, B Ben-Azu, OG Adebayo… - Journal of Molecular …, 2023 - Springer
Social defeat stress (SDS) due to changes in biochemical functions has been implicated in
the pathogenesis of affective and cognitive disorders. Employing pharmacological approach …

Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer's disease-like behavioral rat model

GY Choi, HB Kim, ES Hwang, HS Park, JM Cho… - Neurotoxicology, 2023 - Elsevier
Abstract Alzheimer's disease (AD), as the most typical type of dementia, is a chronic
neurodegenerative disorder characterized by progressive learning and memory impairment …

Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats

GV Ramalingayya, SP Cheruku, PG Nayak… - Drug design …, 2017 - Taylor & Francis
Doxorubicin (DOX) is the most widely used broad-spectrum anticancer agent, either alone or
in combination, for most cancers including breast cancer. Long-term use of …