Rare mutation-dominant compound EGFR-positive NSCLC is associated with enriched kinase domain-resided variants of uncertain significance and poor clinical …
W Zhao, A Song, Y Xu, Q Wu, C Liu, JC Yin, Q Ou… - BMC medicine, 2023 - Springer
Background Compound epidermal growth factor receptor (EGFR) mutations are less
responsive to tyrosine kinase inhibitors (TKIs) than single EGFR mutations in non-small cell …
responsive to tyrosine kinase inhibitors (TKIs) than single EGFR mutations in non-small cell …
Abnormality of apico–basal polarity in adenocarcinoma
K Onuma, M Inoue - Cancer Science, 2022 - Wiley Online Library
Apico–basal polarity is a fundamental property of the epithelium that functions as a barrier,
holds cells together, and determines the directions of absorption and secretion. Apico–basal …
holds cells together, and determines the directions of absorption and secretion. Apico–basal …
Comprehensive analyses unveil novel genomic and immunological characteristics of micropapillary pattern in lung adenocarcinoma
Y Huo, L Sun, J Yuan, H Zhang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Lung adenocarcinoma (LUAD) usually contains heterogeneous histological subtypes,
among which the micropapillary (MIP) subtype was associated with poor prognosis while the …
among which the micropapillary (MIP) subtype was associated with poor prognosis while the …
Association of Molecular Profiles and Mutational Status With Distinct Histological Lung Adenocarcinoma Subtypes. An Analysis of the LACE-Bio Data
Background Adjuvant chemotherapy (AC) is indicated for stage II and stage III lung
adenocarcinomas (ADC). Using the LACE Bio II database, we analyzed the distribution of …
adenocarcinomas (ADC). Using the LACE Bio II database, we analyzed the distribution of …
Whole-exome sequencing reveals the genomic features of the micropapillary component in ground-glass opacities
F Meng, Y Zhang, S Wang, T Liu, M Sun, H Zhu… - Cancers, 2022 - mdpi.com
Simple Summary The micropapillary component in lung adenocarcinoma has a valid
predictive role for patient prognosis. To investigate targeted clinical strategies, we collected …
predictive role for patient prognosis. To investigate targeted clinical strategies, we collected …
High‑risk pathological subtype associated FAM83A‑AS1 promotes malignancy and glycolysis of lung adenocarcinoma via miR‑202‑3p/HK2 axis
X Xiong, L Zhang, B Zang, D Xu… - Oncology …, 2023 - spandidos-publications.com
According to the diverse cellular morphology, lung adenocarcinoma (LUAD) was classified
into five pathological subtypes, referred to as follows: High‑risk group (micropapillary and …
into five pathological subtypes, referred to as follows: High‑risk group (micropapillary and …
Ttc39c is a potential target for the treatment of lung cancer
H Rong, J Peng, K Ma, J Zhu, JT He - BMC Pulmonary Medicine, 2022 - Springer
Background The novel TTC gene, tetratricopeptide repeat domain 39 C (Ttc39c), mainly
mediates the interaction between proteins. It is involved in the progression of various tumors …
mediates the interaction between proteins. It is involved in the progression of various tumors …
Clinical and genetic characteristics in lymphoma patients with a second solid malignancy
D Zhou, L Han, C Jin, L Bi - Frontiers in Oncology, 2023 - frontiersin.org
Diagnosis and treatment of multiple primary malignancies are becoming a new challenge in
clinical practice worldwide. The present study aimed to characterize the clinical and genetic …
clinical practice worldwide. The present study aimed to characterize the clinical and genetic …
Genomic and clinicopathological features of lung adenocarcinomas with micropapillary component
P Li, L Liu, D Wang, R Yang, Y Xuan, Y Han… - Frontiers in …, 2022 - frontiersin.org
Background Lung adenocarcinoma (LA) with a micropapillary component (LAMPC) is a
histological subtype of lung cancer that has received increasing attention due to its …
histological subtype of lung cancer that has received increasing attention due to its …
[HTML][HTML] EGFR co-mutation is associated with the risk of recurrence in invasive lung adenocarcinoma with the micropapillary component
H Kang, H Lv, TH Tung, D Ma, Z Wang, J Du… - Asian Journal of …, 2024 - Elsevier
Background Invasive lung adenocarcinoma (LUAD) patients with the micropapillary (MPP)
component tend to have extremely poor prognosis. To optimize clinical outcomes, a better …
component tend to have extremely poor prognosis. To optimize clinical outcomes, a better …