A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Bioactive potential of natural biomaterials: Identification, retention and assessment of biological properties

K Joyce, GT Fabra, Y Bozkurt, A Pandit - Signal transduction and …, 2021 - nature.com
Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Advances in growth factor delivery for bone tissue engineering

ÉR Oliveira, L Nie, D Podstawczyk… - International journal of …, 2021 - mdpi.com
Shortcomings related to the treatment of bone diseases and consequent tissue regeneration
such as transplants have been addressed to some extent by tissue engineering and …

Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease

O Karayel, SV Winter, S Padmanabhan, YI Kuras… - Cell Reports …, 2022 - cell.com
Parkinson's disease (PD) is a growing burden worldwide, and there is no reliable biomarker
used in clinical routines to date. Cerebrospinal fluid (CSF) is routinely collected in patients …

Glycosaminoglycan–protein interactions: the first draft of the glycosaminoglycan interactome

SD Vallet, O Clerc… - Journal of Histochemistry …, 2021 - journals.sagepub.com
The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate,
heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides …

Natural polysaccharides: Chemical properties and application in pharmaceutical formulations

M Tudu, A Samanta - European Polymer Journal, 2023 - Elsevier
Natural polysaccharides have an important role in pharmaceutical industries and are
considered a huge source and importance. Polysaccharides are biopolymers characterized …

Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING

R Fang, Q Jiang, Y Guan, P Gao, R Zhang, Z Zhao… - Immunity, 2021 - cell.com
Activation of the cyclic guanosine monophosphate (GMP)-AMP (cGAMP) sensor STING
requires its translocation from the endoplasmic reticulum to the Golgi apparatus and …

Glycosaminoglycans and glycosaminoglycan mimetics in cancer and inflammation

S Morla - International journal of molecular sciences, 2019 - mdpi.com
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all
mammalian cells and usually covalently attached to proteins, forming proteoglycans. They …

Glycosaminoglycans in tissue engineering: a review

H Sodhi, A Panitch - Biomolecules, 2020 - mdpi.com
Glycosaminoglycans are native components of the extracellular matrix that drive cell
behavior and control the microenvironment surrounding cells, making them promising …