Glucagon-like peptide 1 receptor agonists and 13 obesity-associated cancers in patients with type 2 diabetes

L Wang, R Xu, DC Kaelber, NA Berger - JAMA Network Open, 2024 - jamanetwork.com
Importance Thirteen human malignant neoplasms have been identified as obesity-
associated cancers (OACs), ie, the presence of excess body fat is associated with increased …

Burden of cancer attributable to obesity, type 2 diabetes and associated risk factors

A López-Suárez - Metabolism, 2019 - Elsevier
Overweight and obesity constitute a global pandemic with devastating consequences that
affect> 2 billion people. Obesity plays a central role in morbidity and mortality of diseases of …

Gut adaptation after metabolic surgery and its influences on the brain, liver and cancer

P Sinclair, DJ Brennan, CW le Roux - Nature reviews Gastroenterology …, 2018 - nature.com
Metabolic surgery is the best treatment for long-term weight loss maintenance and
comorbidity control. Metabolic operations were originally intended to change anatomy to …

Diabetes and cancer: Pathophysiological fundamentals of a 'dangerous affair'

A Cignarelli, VA Genchi, I Caruso, A Natalicchio… - Diabetes research and …, 2018 - Elsevier
Diabetes and cancer are worldwide chronic diseases with a major impact on the quality and
expectancy of life. Metabolic abnormalities observed during the onset and progression of …

[HTML][HTML] The application of lag times in cancer pharmacoepidemiology: a narrative review

B Hicks, JA Kaye, L Azoulay, KB Kristensen… - Annals of …, 2023 - Elsevier
Purpose With the increasing utilization of medications worldwide, coupled with the
increasing availability of long-term data, there is a growing opportunity and need for robust …

GLP-1 receptor agonists and risk of cancer in type 2 diabetes: an updated meta-analysis of randomized controlled trials

C Cao, S Yang, Z Zhou - Endocrine, 2019 - Springer
Purpose Some preliminary studies reported a link between GLP-1 receptor agonists (GLP-
1RAs) and thyroid/pancreatic neoplasms, while its human relevance remained …

Novel treatments for obesity: implications for cancer prevention and treatment

CM Cuttica, IM Briata, A DeCensi - Nutrients, 2023 - mdpi.com
It is now established that obesity is related to a higher incidence of cancer during a lifespan.
The effective treatment of obesity opens up new perspectives in the treatment of a relevant …

Side effects associated with liraglutide treatment for obesity as well as diabetes

YG Seo - Journal of Obesity & Metabolic Syndrome, 2020 - pmc.ncbi.nlm.nih.gov
Liraglutide is a glucagon-like peptide-1 receptor agonist used as a treatment for type 2
diabetes mellitus, which has been expanded for use at a higher dose in weight control …

Neoplasms reported with liraglutide or placebo in people with type 2 diabetes: results from the LEADER randomized trial

MA Nauck, TJ Jensen, C Rosenkilde, S Calanna… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE This study explored neoplasm risk with liraglutide versus placebo in the
LEADER (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome …

Risk of dipeptidyl peptidase‐4 (DPP‐4) inhibitors on site‐specific cancer: A systematic review and meta‐analysis

JA Overbeek, M Bakker… - Diabetes/metabolism …, 2018 - Wiley Online Library
The long‐term impact of dipeptidyl peptidase‐4 (DPP‐4) inhibition is unknown, and there
are concerns about the influence of DPP‐4 inhibition on carcinogenesis of the pancreas and …