Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

G Livingston, J Huntley, A Sommerlad, D Ames… - The lancet, 2020 - thelancet.com
Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Rationale for a multi-factorial approach for the reversal of cognitive decline in Alzheimer's disease and MCI: a review

RV Rao, KG Subramaniam, J Gregory… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disease
typically characterized by memory loss, personality changes, and a decline in overall …

Virtual reality to promote wellbeing in persons with dementia: A scoping review

L Appel, S Ali, T Narag, K Mozeson… - … of rehabilitation and …, 2021 - journals.sagepub.com
Virtual Reality (VR) technologies have increasingly been considered potentially valuable
tools in dementia-related research and could serve as non-pharmacological therapy to …

Toward a theory‐based specification of non‐pharmacological treatments in aging and dementia: focused reviews and methodological recommendations

SAM Sikkes, Y Tang, RJ Jutten… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Introduction Non‐pharmacological treatments (NPTs) have the potential to improve
meaningful outcomes for older people at risk of, or living with dementia, but research often …

Bridging the divide between biomedical and psychosocial approaches in dementia research: the 2019 INTERDEM manifesto

M Vernooij-Dassen, E Moniz-Cook, F Verhey… - Aging & Mental …, 2021 - Taylor & Francis
Objective To provide a new perspective on integrated biomedical and psychosocial
dementia research. Background Dementia is being recognized as a multifactorial syndrome …

Exploring the bi‐directional relationship between autophagy and Alzheimer's disease

H Kuang, CY Tan, HZ Tian, LH Liu… - CNS neuroscience & …, 2020 - Wiley Online Library
Alzheimer's disease (AD) is characterized by β‐amyloid (Aβ) deposition and Tau
phosphorylation, in which its pathogenesis has not been cleared so far. The metabolism of …

Do caregiver interventions improve outcomes in relatives with dementia and mild cognitive impairment? A comprehensive systematic review and meta-analysis.

ST Cheng, KK Li, PPL Or, A Losada - Psychology and Aging, 2022 - psycnet.apa.org
Some reviews suggest benefits of nonpharmacological interventions for informal caregivers
of people with dementia and mild cognitive impairment. These benefits may transfer to the …

Cognitive rehabilitation for people with mild to moderate dementia

A Kudlicka, A Martyr, A Bahar-Fuchs… - Cochrane Database …, 2023 - cochranelibrary.com
Background Cognitive impairments affect functional ability in people with dementia.
Cognitive rehabilitation (CR) is a personalised, solution‐focused approach that aims to …

The role of physical and cognitive function in performance of activities of daily living in patients with mild-to-moderate Alzheimer's disease–a cross-sectional study

FK Clemmensen, K Hoffmann, V Siersma, N Sobol… - BMC geriatrics, 2020 - Springer
Background Several factors may play a role in the ability of patients with Alzheimer's disease
to perform activities of daily living (ADL). The aim of this study was to examine the impact of …

ABCA1‐Labeled Exosomes in Serum Contain Higher MicroRNA‐193b Levels in Alzheimer's Disease

CG Liu, Y Zhao, Y Lu, PC Wang - BioMed Research …, 2021 - Wiley Online Library
Objective. We aimed to establish a method to determine whether microRNA‐193b (miR‐
193b) levels in ABCA1‐labeled serum exosomes might serve as a marker for the diagnosis …