Biological activities of hydrazone derivatives

S Rollas, Ş Güniz Küçükgüzel - Molecules, 2007 - mdpi.com
There has been considerable interest in the development of novel compounds with
anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, anti-malarial …

Mini-review of the importance of hydrazides and their derivatives—Synthesis and biological activity

SN Mali, BR Thorat, DR Gupta, A Pandey - Engineering proceedings, 2021 - mdpi.com
Organic acid hydrazides include a vast group of organic derivatives of hydrazines containing
the active functional group (-C (= O) NHNH2). Acid hydrazones were important bidentate …

Synthesis and characterization of novel hydrazide–hydrazones and the study of their structure–antituberculosis activity

KK Bedia, O Elçin, U Seda, K Fatma, S Nathaly… - European journal of …, 2006 - Elsevier
A series of hydrazide–hydrazones, based on a series of 4-substituted benzoic acid, were
synthesized, and their structures were elucidated and screened for the antituberculosis …

Synthesis of new hydrazones using a biodegradable catalyst, their biological evaluations and molecular modeling studies (Part-II)

SN Mali, A Pandey - Journal of Computational Biophysics and …, 2022 - World Scientific
Hydrazones typically have an azomethine '–NHN= CH group'which is crucial for varieties of
pharmacological activities. In this study, we have synthesized a set of 15 new hydrazones …

Synthesis and biological activity of hydrazones and derivatives: A review

J de Oliveira Carneiro Brum… - Mini reviews in …, 2020 - ingentaconnect.com
Hydrazones and their derivatives are very important compounds in medicinal chemistry due
to their reported biological activity for the treatment of several diseases, like Alzheimer's …

Fighting tuberculosis: an old disease with new challenges

RP Tripathi, N Tewari, N Dwivedi… - Medicinal Research …, 2005 - Wiley Online Library
Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a leading cause of
mortality worldwide into 21st century. The mortality and spread of this disease has further …

Recent advances in new structural classes of anti-tuberculosis agents

A Nayyar, SR Patel, R Jain - Frontiers in Medicinal Chemistry …, 2009 - benthamdirect.com
Tuberculosis (TB) is one of the most devastating diseases primarily due to several decades
of neglect and presents a global health threat of escalating proportions. TB is second …

[PDF][PDF] Anti-tubercular activity of isatin derivatives

T Aboul-Fadl, FAS Bin-Jubair - Int. J. Res. Pharm. Sci, 2010 - academia.edu
Tuberculosis TB re ai saog the orld s great public health challenges. Worldwide resurgence
of TB is due to two major problems: the acquired immunodeficiency syndrome (AIDS) …

Synthesis, admetSAR predictions, DPPH radical scavenging activity, and potent anti-mycobacterial studies of hydrazones of substituted 4-(anilino methyl) …

VJ Desale, SN Mali, BR Thorat… - … Computer-Aided Drug …, 2021 - ingentaconnect.com
Background: For the past several decades, the presence of tuberculosis (TB) is being
remarked as the most common infectious disease leading to mortality. Objective: Hydrazone …

Synthesis, molecular docking, antioxidant, anti-TB, and potent MCF-7 anticancer studies of novel aryl-carbohydrazide analogues

B R. Thorat, S N. Mali, R R. Wagh… - … Computer-Aided Drug …, 2022 - benthamdirect.com
Background: Hydrazide-hydrazone-based compounds are reported for their wider
pharmacological potentials. Methods: In the present work, we synthesized 10 new Schiff …