Epidemiology of IgA nephropathy: a global perspective

FP Schena, I Nistor - Seminars in nephrology, 2018 - Elsevier
IgA nephropathy (IgAN), or Berger's disease, is the most common primary glomerular
disease worldwide, but varies largely in its geographic distribution. A systematic review of …

The next generation of therapeutics for chronic kidney disease

MD Breyer, K Susztak - Nature reviews Drug discovery, 2016 - nature.com
Chronic kidney disease (CKD) represents a leading cause of death in the United States.
There is no cure for this disease, with current treatment strategies relying on blood pressure …

APOL1 risk variants are strongly associated with HIV-associated nephropathy in black South Africans

AN Kasembeli, R Duarte, M Ramsay… - Journal of the …, 2015 - journals.lww.com
APOL1 variants are associated with HIV-associated nephropathy and FSGS in African
Americans. The prevalence of these variants in African populations with CKD in HIV-1 …

The genetics and immunobiology of IgA nephropathy

K Kiryluk, J Novak - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
IgA nephropathy (IgAN) represents the leading cause of kidney failure among East Asian
populations and the most frequent form of primary glomerulonephritis among Europeans …

Primary nephrotic syndrome and risks of ESKD, cardiovascular events, and death: the Kaiser Permanente nephrotic syndrome study

AS Go, TC Tan, GM Chertow, JD Ordonez… - Journal of the …, 2021 - journals.lww.com
Methods To evaluate kidney, cardiovascular, and mortality outcomes in adults with primary
nephrotic syndrome, we identified adults within an integrated health care delivery system …

Autophagy and mitophagy: physiological implications in kidney inflammation and diseases

D Bhatia, ME Choi - American Journal of Physiology-Renal …, 2023 - journals.physiology.org
Autophagy is a ubiquitous intracellular cytoprotective quality control program that maintains
cellular homeostasis by recycling superfluous cytoplasmic components (lipid droplets …

Incidence of remission and relapse of proteinuria, end-stage kidney disease, mortality, and major outcomes in primary nephrotic syndrome: the Japan Nephrotic …

R Yamamoto, E Imai, S Maruyama… - Clinical and …, 2020 - Springer
Background Despite recent advances in immunosuppressive therapy for patients with
primary nephrotic syndrome, its effectiveness and safety have not been fully studied in …

Primary glomerular diseases and long‐term adverse health outcomes: A nationwide cohort study

AL Faucon, S Lando, C Chrysostomou… - Journal of internal …, 2024 - Wiley Online Library
Background Although glomerular diseases are the third most frequent cause of end‐stage
kidney disease worldwide, little is known about their long‐term outcomes. Methods In …

Patient characteristics and outcomes by GN subtype in ESRD

MM O'Shaughnessy, ME Montez-Rath… - Clinical Journal of the …, 2015 - journals.lww.com
Results Among 84,301 patients with ESRD attributed to GN, the median age ranged from 39
(LN) to 66 (vasculitis) years, male sex ranged from 18%(LN) to 68%(IgAN), and black race …

Mortality and renal outcome of primary glomerulonephritis in Korea: observation in 1,943 biopsied cases

H Lee, DK Kim, KH Oh, KW Joo, YS Kim… - American journal of …, 2013 - karger.com
Background: Previous epidemiological studies have focused on the prevalence of primary
glomerulonephritis (GN), but few have explored long-term patient outcomes. This study was …