Preeclampsia is a life-threatening complication that develops in 2-8% of pregnancies. It is
characterized by elevated blood pressure after 20 weeks of gestation and may progress to …

Preeclampsia is a pregnancy-specific disease that has no known precise cause. Integrative
biology approach based on multi-omics has been applied to identify upstream pathways and …

BACKGROUND: Preeclampsia, a pregnancy-specific condition associated with new-onset
hypertension after 20-weeks gestation, is a leading cause of maternal and neonatal …

Inexpensive and accurate genotyping methods are essential to modern genomics and
health risk prediction. Here we introduce QUILT2, a scalable read-aware imputation method …

Background: Hypertension and hypertensive disorders of pregnancy (HDP) cause a
significant burden of disease on societies and individuals by increasing cardiovascular …

Genetic factors related to pregnancy-related traits are understudied, especially in ancestrally
diverse cohorts. To assess maternal contributions to hypertensive disorders of pregnancy …

Background: Genomic information from pregnant women and their husbands may provide
effective biomarkers for preeclampsia. This study investigated how parental polygenic risk …

Saccular intracranial aneurysms (sIAs) are pouches that form on the intracranial arteries
during life and usually go unnoticed. However, a rupture of the sIA wall, the most common …

Introduction: It is still difficult to identify women who are more likely to develop preeclampsia,
even after decades of research into the condition. Determining whether women are" at-risk" …

Preeclampsia, a pregnancy complication characterized by hypertension after 20 gestational
weeks, is a major cause of maternal and neonatal morbidity and mortality. Mechanisms …