Obesity has become one of the main threats to health worldwide and therefore gained
increasing clinical and economic significance as well as scientific attention. General adipose …

Crohn's disease (CD) is a complex gastrointestinal disorder involving multiple levels of cross
talk between the immunological, neural, vascular, and endocrine systems. The current …

We investigated the relationship between gut health, visceral fat dysfunction and metabolic
disorders in diet-induced obesity. C57BL/6J mice were fed control or high saturated fat diet …

Methotrexate (MTX), a chemotherapeutic antimetabolite, has been linked to cognitive
impairment in cancer patients. MTX-induced metabolic pathway disruption may result in …

Obesity and diabetes are rapidly increasing in both developed and developing countries
with enormous personal and economic cost implications. Type 2 diabetes was recognized …

In the last two decades we have witnessed a boost in scientific interest and knowledge of
adipose tissue biology to such an extent that it was promoted to an active endocrine organ …

In this study, we investigated the effects and the protective mechanism of ginsenoside Rd
(GRd) which has been identified as one of the effective compounds from ginseng on …

Sishen Pill (SSP) is a classical prescription of traditional Chinese medicine and often used
to treat gastrointestinal diseases, including ulcerative colitis (UC). However, its mechanism …

Background & aims Mesenteric adipose tissue hypertrophy is a hallmark of Crohn's disease
and can express various adipokines. Exclusive enteral nutrition could effectively induce …

Adiponectin and resistin, members of the adipokine family, are multi-task hormones involved
in several disorders, including those of the alimentary tract. In the present review, eligible …