Structurally diverse pyridinium salts are quite familiar structures in many natural products
and bioactive pharmaceuticals. Over the centuries, these privileged scaffolds have played …

Gene therapy, as a promising therapeutics to treat genetic or acquired diseases, has
achieved exciting development in the past two decades. Appropriate gene vectors can be …

Cationic lipids are one of the most widely used nonviral vectors for gene delivery and are
especially attractive because they can be easily synthesized and extensively characterized …

Gene transfer represents an important advance in the treatment of both genetic and
acquired diseases. Many cationic lipids and cationic polymers naturally occurred or …

Synthetic gene delivery vectors are gaining increasing importance in gene therapy as an
alternative to recombinant viruses. Among the various types of non-viral vectors, cationic …

Gene therapy research is still in trouble owing to a paucity of acceptable vector systems to
deliver nucleic acids to patients for therapy. Viral vectors are efficient but may be too …

The effectiveness of messenger RNA (mRNA) vaccines, especially those designed for
COVID-19, relies heavily on sophisticated delivery systems that ensure efficient delivery of …

Self-assembled synthetic gene delivery systems represent the bottom-up approach to gene
delivery and gene silencing, in which scientists are designing novel cationic and procationic …

Several new classes of pyridinium cationic lipids were synthesized and tested as gene
delivery agents. They were obtained through a procedure that generates simultaneously the …

Gemini surfactants (GS) are presently receiving substantial attention due to their special self‐
assembling properties and unique interfacial activity. This comprehensive review is focused …