Biomarkers in psychiatry: concept, definition, types and relevance to the clinical reality

MS García-Gutiérrez, F Navarrete, F Sala… - Frontiers in …, 2020 - frontiersin.org
During the last years, an extraordinary effort has been made to identify biomarkers as
potential tools for improving prevention, diagnosis, drug response and drug development in …

Adverse childhood experiences are associated with reduced psychological resilience in youth: A systematic review and meta-analysis

CA Morgan, YH Chang, O Choy, MC Tsai, S Hsieh - Children, 2021 - mdpi.com
Background: Adverse childhood experiences (ACEs) are presumed to influence
internalizing and externalizing behaviors that can significantly debilitate long-term …

Neuropeptide Y is an immunomodulatory factor: direct and indirect

W Chen, Y Liu, W Liu, Y Zhou, H He, S Lin - Frontiers in immunology, 2020 - frontiersin.org
Neuropeptide Y (NPY), which is widely distributed in the nervous system, is involved in
regulating a variety of biological processes, including food intake, energy metabolism, and …

The role of epigenetics in psychological resilience

D Smeeth, S Beck, EG Karam, M Pluess - The Lancet Psychiatry, 2021 - thelancet.com
There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …

Gender differences in depression: evidence from genetics

L Zhao, G Han, Y Zhao, Y Jin, T Ge, W Yang… - Frontiers in …, 2020 - frontiersin.org
Compared with men, female accounts for a larger proportion of patients with depression.
Behavioral genetics researches find gender differences in genetic underpinnings of …

The molecular basis of resilience: a narrative review

M Ryan, R Ryznar - Frontiers in Psychiatry, 2022 - frontiersin.org
Resilience refers to the adaptability of a person–an ability to “bounce-back” from stressors.
We question if resilience can be strengthened, potentially to decrease the risk of stress …

Coping and resilience in adults: a cross-sectional network analysis

R Van der Hallen, J Jongerling… - Anxiety, Stress, & …, 2020 - Taylor & Francis
Background and objectives: Coping and resilience, how we deal with problems and
difficulties and recover from misfortune or change, are two well-known interrelated concepts …

Impact of acute and chronic stress on thrombosis in healthy individuals and cardiovascular disease patients

L Sandrini, A Ieraci, P Amadio, M Zarà… - International journal of …, 2020 - mdpi.com
Psychological stress induces different alterations in the organism in order to maintain
homeostasis, including changes in hematopoiesis and hemostasis. In particular, stress …

Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder

C Snijders, AX Maihofer, A Ratanatharathorn… - Clinical …, 2020 - Springer
Background Epigenetic mechanisms have been suggested to play a role in the development
of post-traumatic stress disorder (PTSD). Here, blood-derived DNA methylation data …

What doesn't kill us makes us stronger: insights from neuroscience studies and molecular genetics

Y Gan, H Huang, X Wu, M Meng - Current Opinion in Behavioral Sciences, 2024 - Elsevier
Highlights•Neural mechanisms underlying stress and resilience are discussed.•Genetic
factors may partially determine why only some individuals develop resilience.•Machine …