The biggest compartment of the musculoskeletal system is the tendons and ligaments. In
particular, tendons are dense tissues connecting muscle to bone that are critical for the …

Degenerative orthopedic diseases, as a global public health problem, have made serious
negative impact on patients' quality of life and socio-economic burden. Traditional …

Sports genomics is the scientific discipline that focuses on the organization and function of
the genome in elite athletes, and aims to develop molecular methods for talent identification …

The role of inflammation in tendon injury is uncertain and a topic of current interest. In vitro
studies of tendon accelerated overload damage can serve as a valuable source of …

Abstract Background Tendon-ligament injuries (TLIs), including Achilles tendinopathy,
cruciate ligament injury, tennis elbow, rotator cuff injury, patellar tendinopathy, and tibial …

Background. Mesenchymal stem cells (MSCs) emerged as a promising therapy for tendon
pathologies. Microfragmented adipose tissue (μFAT) represents a convenient autologous …

To date, more than 18 genomic intervals, which underpin the complex myriad of extracellular
matrix interactions of tendons, have been implicated in risk models for tendinopathy. It is …

The evidence implicating genetics in the susceptibility to musculoskeletal soft tissue injuries
is growing, with over 80 risk-conferring loci discovered to date. Primarily through the …

Abstract Matrix metalloproteinase-1 (MMP-1) has been implicated in several inflammatory
and fibrotic diseases. We hypothesized that genetic variations in the MMP1 promoter region …

The aim of the study was to investigate whether genetic variants in VEGF and KDR genes
can be correlated with susceptibility of tendinopathy in volleyball athletes. This study was …