Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of
local diseases such as ulcerative colitis, Crohn's disease, irritable bowel syndrome, chronic …

The intestinal microbiota is a preponderant mediator of dietary effects on host health,
through the metabolism of undigested dietary macronutrients. Gut microbial metabolism …

In case of colon-specific delivery of therapeutic agents through oral route, microbial/enzyme-
triggered release approach has several advantages over other approaches due to unique …

Swelling agents are hydrophilic crosslinked polymers, which swell from 10 to 1,000 times
their own weight when placed in an aqueous medium. Depending on their swelling …

Microcrystalline cellulose (MCC) is one of the most popular cellulose derivatives in the
pharmaceutical industry. Thanks to its outstanding tabletability, MCC is generally included in …

Colon specific drug delivery has gained increased importance not just for the delivery of
drugs for the treatment of local diseases associated with the colon but also as potential site …

Ulcerative colitis is the chronic relapsing multifactorial gastrointestinal inflammatory bowel
disease, which is characterized by bloody or mucus diarrhea, tenesmus, bowel dystension …

The purpose of the present investigation was to prepare matrix tablets of naproxen using a
hydrophobic polymer, ie, Eudragit RLPO, RSPO, and combination of both, by wet …

In recent years, many research efforts have been spent in the achievement of selective
delivery of drugs into the colon following oral administration. Indeed, colonic release is …

Oral colon delivery is pursued through a number of formulation strategies with the aim of
enabling effective and well-tolerated treatments for large bowel pathologies or enhancing …