Blood cells separation and sorting techniques of passive microfluidic devices: From fabrication to applications

SO Catarino, RO Rodrigues, D Pinho, JM Miranda… - Micromachines, 2019 - mdpi.com
Since the first microfluidic device was developed more than three decades ago, microfluidics
is seen as a technology that exhibits unique features to provide a significant change in the …

Elevating chemistry research with a modern electronics toolkit

GRD Prabhu, PL Urban - Chemical Reviews, 2020 - ACS Publications
With the rapid development of high technology, chemical science is not as it used to be a
century ago. Many chemists acquire and utilize skills that are well beyond the traditional …

Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin

ER Henry, B Metaferia, Q Li, J Harper… - Blood, The Journal …, 2021 - ashpublications.org
The issue of treating sickle cell disease with drugs that increase hemoglobin oxygen affinity
has come to the fore with the US Food and Drug Administration approval in 2019 of …

Network-driven anomalous transport is a fundamental component of brain microvascular dysfunction

F Goirand, T Le Borgne, S Lorthois - Nature communications, 2021 - nature.com
Blood microcirculation supplies neurons with oxygen and nutrients, and contributes to
clearing their neurotoxic waste, through a dense capillary network connected to larger tree …

Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease

B Metaferia, T Cellmer… - Proceedings of the …, 2022 - National Acad Sciences
Stem cell transplantation and genetic therapies offer potential cures for patients with sickle
cell disease (SCD), but these options require advanced medical facilities and are expensive …

Flat and microstructured polymeric membranes in organs-on-chips

T Pasman, D Grijpma… - Journal of the Royal …, 2018 - royalsocietypublishing.org
In recent years, organs-on-chips (OOCs) have been developed to meet the desire for more
realistic in vitro cell culture models. These systems introduce microfluidics, mechanical …

Heavy metal toxicity in Buriganga river alters the immunology of Nile tilapia (Oreochromis niloticus L)

Z Hossain, MS Hossain, NS Ema, A Omri - Heliyon, 2021 - cell.com
The objective of the current study was to evaluate the biochemical and immunological
responses of tilapia, Oreochromis niloticus due to heavy metals pollution …

Remote ischemic conditioning enhances oxygen supply to ischemic brain tissue in a mouse model of stroke: Role of elevated 2, 3-biphosphoglycerate in erythrocytes

L Wang, C Ren, Y Li, C Gao, N Li, H Li… - Journal of Cerebral …, 2021 - journals.sagepub.com
Oxygen supply for ischemic brain tissue during stroke is critical to neuroprotection. Remote
ischemic conditioning (RIC) treatment is effective for stroke. However, it is not known …

Development of porous and flexible PTMC membranes for in vitro organ models fabricated by evaporation-induced phase separation

T Pasman, D Baptista, S van Riet, RK Truckenmüller… - Membranes, 2020 - mdpi.com
Polymeric membranes are widely applied in biomedical applications, including in vitro organ
models. In such models, they are mostly used as supports on which cells are cultured to …

[HTML][HTML] On-chip spectroscopic monitoring of erythrocyte oxygenation under hematocrit and oxygen gradients

R Dong, Y Li, S Liu, W Li, L Tao, C Chen, Z Qian… - Journal of Science …, 2022 - Elsevier
The interpretation of the variability and determinants of erythrocyte oxygenation is
complicated by multiple interacting factors manifesting gaseous and fluidic …