Autoantibody specificities in myasthenia gravis; implications for improved diagnostics and therapeutics

K Lazaridis, SJ Tzartos - Frontiers in immunology, 2020 - frontiersin.org
Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness and
fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by …

Myasthenia gravis—autoantibody characteristics and their implications for therapy

NE Gilhus, GO Skeie, F Romi, K Lazaridis… - Nature reviews …, 2016 - nature.com
Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies that target the
neuromuscular junction, leading to muscle weakness and fatigability. Currently available …

Diagnosis and management of myocardial involvement in systemic immune-mediated diseases: a position statement of the European Society of Cardiology Working …

ALP Caforio, Y Adler, C Agostini, Y Allanore… - European heart …, 2017 - academic.oup.com
Systemic immune-mediated diseases (SIDs) include autoimmune and autoinflammatory
diseases (AD) affecting at least two-organ systems. 1 Autoinflammatory diseases refer to a …

Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies

PE Lazzerini, F Laghi-Pasini, M Boutjdir… - Nature Reviews …, 2019 - nature.com
Fig. 1| Autoimmune and inflammatory cardiac channelopathies and arrhythmias: molecular
basis. Autoantibodies and inflammatory cytokines can modulate the function of cardiac ion …

Long QT syndrome: an emerging role for inflammation and immunity

PE Lazzerini, PL Capecchi… - Frontiers in cardiovascular …, 2015 - frontiersin.org
The long QT syndrome (LQTS), classified as congenital or acquired, is a multi-factorial
disorder of myocardial repolarization predisposing to life-threatening ventricular …

Myasthenia gravis and risks for comorbidity

NE Gilhus, A Nacu, JB Andersen… - European journal of …, 2015 - Wiley Online Library
Myasthenia gravis (MG) is an autoimmune disorder leading to skeletal muscle weakness
and fatigability. MG subgroups are defined according to pathogenetic autoantibody (against …

Myasthenia gravis: autoantibody specificities and their role in MG management

K Lazaridis, SJ Tzartos - Frontiers in neurology, 2020 - frontiersin.org
Myasthenia gravis (MG) is the most common autoimmune disorder affecting the
neuromuscular junction, characterized by skeletal muscle weakness and fatigability. It is …

Emerging arrhythmic risk of autoimmune and inflammatory cardiac channelopathies

PE Lazzerini, PL Capecchi, N El‐Sherif… - Journal of the …, 2018 - Am Heart Assoc
Cardiac arrhythmias are associated with high morbidity and mortality. 1 Specifically,
malignant arrhythmias are a recognized leading cause of sudden cardiac death (SCD) in the …

Complicating autoimmune diseases in myasthenia gravis: a review

A Nacu, JB Andersen, V Lisnic, JF Owe, NE Gilhus - Autoimmunity, 2015 - Taylor & Francis
Myasthenia gravis (MG) is a rare autoimmune disease of skeletal muscle endplates. MG
subgroup is relevant for comorbidity, but usually not accounted for. MG patients have an …

Autoimmune channelopathies as a novel mechanism in cardiac arrhythmias

PE Lazzerini, PL Capecchi, F Laghi-Pasini… - Nature Reviews …, 2017 - nature.com
Cardiac arrhythmias confer a considerable burden of morbidity and mortality in
industrialized countries. Although coronary artery disease and heart failure are the prevalent …