Organelle-targeted photosensitizers for precision photodynamic therapy

R Wang, X Li, J Yoon - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …

[HTML][HTML] Photoimmunotherapy of ovarian cancer: a unique niche in the management of advanced disease

S Nath, MA Saad, M Pigula, JWR Swain, T Hasan - Cancers, 2019 - mdpi.com
Ovarian cancer (OvCa) is the leading cause of gynecological cancer-related deaths in the
United States, with five-year survival rates of 15–20% for stage III cancers and 5% for stage …

Biocompatible and nanoenabled technologies for biological modulation

E Ostroff, K Parekh, A Prominski… - Advanced Materials …, 2022 - Wiley Online Library
Biocompatible and nanoscale devices for biological modulation of cells and tissues possess
the potential for tremendous impact on medical and industrial technologies. Typical medical …

Photodynamic therapy by lysosomal-targeted drug delivery using talaporfin sodium incorporated into inactivated virus particles

S Akter, M Inai, S Saito, N Honda, H Hazama… - Laser therapy, 2019 - jstage.jst.go.jp
Background: Photodynamic therapy (PDT), a minimally invasive cancer treatment involving
the activation of photosensitizer by a specific wavelength of light, is considered to be a …

Efficient photodynamic therapy against drug-resistant prostate cancer using replication-deficient virus particles and talaporfin sodium

S Akter, S Saito, M Inai, N Honda, H Hazama… - Lasers in Medical …, 2021 - Springer
To enhance the potency of photosensitizer, we developed a novel photosensitizer,
Laserphyrin®-HVJ-E (L-HVJ-E), by incorporating talaporfin sodium (Laserphyrin®, Meiji …

In silico analysis of the association of hsa-miR-16 expression and cell survival in MDA-MB-231 breast cancer cells subjected to photodynamic therapy

MG Cupido-Sánchez, NE Herrera-González… - Photodiagnosis and …, 2021 - Elsevier
Background Breast cancer is the most common malignancy effecting women, and the triple-
negative breast cancer (TNBC) subtype is particularly aggressive. This study aimed to …

Highly selective photodynamic therapy with a short drug-light interval using a cytotoxic photosensitizer porphyrus envelope for drug-resistant prostate cancer cells

Y Hong, M Inai, N Honda… - … Journal of Clinical …, 2018 - research.sdpublishers.net
Background: Photodynamic therapy (PDT) is a less invasive cancer treatment using
photochemical reactions induced by light irradiation to a photosensitizer (PS). Highly …

[PDF][PDF] Cytotoxic mechanism of membrane targeting

稲井, 瑞穂 - 2018 - ir.library.osaka-u.ac.jp
Abstract Development of prostate specific antigen screening has resulted in dramatic
reduction in overall prostate cancer mortality. Survival improvement of advanced-stage …