Candida albicans is the most implicated fungal species that grows as a commensal or
opportunistic pathogen in the human host. It is associated with many life-threatening …

Fungi were some of the earliest organismal systems used to explore mutational processes
and its phenotypic consequences on members of a species. Yeasts that cause significant …

Recently developed transgenic techniques to explore and exploit the metabolic potential of
microalgae present several drawbacks associated with the delivery of exogenous DNA into …

Elucidating population structure and levels of genetic diversity and recombination is
necessary to understand the evolution and adaptation of species. Candida albicans is the …

Candida albicans is a heterozygous diploid yeast that is a commensal of the human
gastrointestinal tract and a prevalent opportunistic pathogen. Here, whole-genome …

We have created new vectors for clustered regularly interspaced short palindromic repeat
(CRISPR) mutagenesis in Candida albicans, Saccharomyces cerevisiae, Candida glabrata …

In vitro studies suggest that stress may generate random standing variation and that different
cellular and ploidy states may evolve more rapidly under stress. Yet this idea has not been …

Loss of heterozygosity (LOH) is a mitotic recombination event that converts heterozygous
loci to homozygous loci. This mutation event is widespread in organisms that have asexual …

The opportunistic fungal pathogen Candida albicans lacks a conventional sexual program
and is thought to evolve, at least primarily, through the clonal acquisition of genetic changes …

Saccharomyces cerevisiae and Schizosaccharomyces pombe have served as uncontested
unicellular model organisms, as major discoveries made in the field of genome biology …