Localisation of proteins of iron metabolism in the human placenta and liver

J Bastin, H Drakesmith, M Rees… - British journal of …, 2006 - Wiley Online Library
Two anatomical sites that are important in human iron metabolism are the liver and placenta.
Liver macrophages recycle iron from erythrocytes, and the placenta transfers iron from the …

Iron chelation beyond transfusion iron overload

A Pietrangelo - American journal of hematology, 2007 - Wiley Online Library
The effects of systemic iron overload in hereditary (eg, classic HFE hemochromatosis) or
acquired disorders (eg, transfusion‐dependent iron overload) are well known. Several other …

The unfolded protein response in hereditary haemochromatosis

SF De Almeida, M De Sousa - Journal of cellular and molecular …, 2008 - Wiley Online Library
To cope with the accumulation of unfolded or misfolded proteins the endoplasmic reticulum
(ER) has evolved specific signalling pathways collectively called the unfolded protein …

HFE cross-talks with the MHC class I antigen presentation pathway

SF De Almeida, IF Carvalho, CS Cardoso, JV Cordeiro… - Blood, 2005 - ashpublications.org
HFE is a protein known to be involved in iron metabolism; yet, other than its homology with
major histocompatibility complex (MHC) class I molecules, it has not been described as …

Estimation of copper and iron burden in biological samples of various stages of hepatitis C and liver cirrhosis patients

SA Arain, TG Kazi, HI Afridi, FN Talpur… - Biological trace element …, 2014 - Springer
There is accumulative evidence that the metabolism of iron (Fe) and copper (Cu) is altered
in human due to infections, indicating that both elements have roles in pathogenesis and …

Relationship between Kuppfer cells, inflammation, and fibrosis in chronic hepatitis B and C

N Stanculet, A Grigoras, R Avadanei… - The Medical-Surgical …, 2013 - revmedchir.ro
Kupffer cells are liver parenchymal components of the immune system able of intervention in
pathogenic mechanisms involved in viral hepatitis and tumoral lesions. Our study aimed to …

[PDF][PDF] Хронический гепатит С и резидентные макрофаги печени

АГ Шевалдин - Фундаментальные исследования, 2010 - s.fundamental-research.ru
Вирусный гепатит С, как известно, проявляет высокую склонность к хронизации и
трансформации в цирроз и первичную гепатокарциному. Попытки определить темпы и …

[HTML][HTML] Serum levels of trace elements in Egyptian patients with chronic hepatitis C under interferon therapy

MA Mohammed, MD El-dien Abd Elmaksoud… - Journal of Genetic …, 2012 - Elsevier
The relationships between chronic liver diseases and trace heavy metal contents in blood
are debatable and have not been understood clearly. The present study was designed to …

Investigation of alteration in the levels of iron and copper in scalp hair samples of patients having different types of viral hepatitis

SA Arain, HI Afridi, TG Kazi, FN Talpur, F Shah… - Biological trace element …, 2013 - Springer
The aim of this study was to measure the alterations of copper and iron contents in scalp hair
samples of hepatitis A–E patients of both genders, same age group, and socioeconomic …

Lymphocyte subset characterization associated with persistent hepatitis C virus infection and subsequent progression of liver fibrosis

K Yoshida, W Ohishi, E Nakashima, S Fujiwara… - Human Immunology, 2011 - Elsevier
This study aims to deepen the understanding of lymphocyte phenotypes related to the
course of hepatitis C virus (HCV) infection and progression of liver fibrosis in a cohort of …