Pharmaceutical compositions for antihypertensive treatments: A patent review

TF Kellici, G Liapakis, AG Tzakos… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: New drug formulations against hypertension have a vital role in the quality of
human life, as this risk factor for cardiovascular disease can be life threatening. A modern …

Oral solid self-nanoemulsifying drug delivery systems of candesartan citexetil: formulation, characterization and in vitro drug release studies

HH Ali, AA Hussein - AAPS Open, 2017 - Springer
Candesartan cilexetil is an ester prodrug antagonist to angiotensin II receptor type 1 (AT1)
used in management of many cardiovascular diseases. The absolute bioavailability of …

The effect of PAMAM dendrimer concentration, generation size and surface functional group on the aqueous solubility of candesartan cilexetil

AS Ertürk, MU Gürbüz, M Tülü - Pharmaceutical development and …, 2017 - Taylor & Francis
This article investigates the aqueous solubility of the poorly soluble drug candesartan
cilexetil (CC) in the presence of poly (amidoamine)(PAMAM) dendrimers. The effect of …

Formulation and bioavailability of novel mucoadhesive buccal films for candesartan cilexetil in rats

OY Mady, MMA Abulmeaty, AA Donia, AA Al-Khureif… - Membranes, 2021 - mdpi.com
Candesartan cilexetil (CC) is an antihypertensive drug. It has low solubility and faces
hepatic first-pass metabolism after oral ingestion. We formulated bioadhesive buccal films …

[PDF][PDF] Enhancement of solubility of a poorly soluble antiplatelet aggregation drug by cogrinding technique

AA Bayoumi - Asian J Pharm Clin Res, 2018 - researchgate.net
Objective: The goal of this study was to formulate ticagrelor tablets with enhanced
dissolution rate using cogrinding technique. However, it belongs to the biopharmaceutical …

[PDF][PDF] Quality control testing of conventional clopidogrel bisulfate tablets marketed in Iraq

MH AL-GBURI - Int J App Pharm, 2022 - pdfs.semanticscholar.org
Objective: This study was employed to evaluate the quality of marketed oral tablets
containing clopidogrel bisulfate. Tablets produced by various companies and …

[PDF][PDF] Evaluation of callinectes chitosan as a superdisintegrant in metronidazole tablet

EO Olorunsola, MO Adedokun… - International Journal of …, 2017 - academia.edu
Objective: The objective of this study is to evaluate callinectes chitosan as a
superdisintegrant in tablet formulation; superdisintegrants are incorporated into tablets at …

[PDF][PDF] Development of binary and ternary complex of cefuroxime axetil with cyclodextrin for improving pharmaceutical characteristics

S Kaushik, R Verma, D Purohit, P Pandey… - Int. J. Appl …, 2020 - academia.edu
Objective: The current research objective is systematic development and characterization of
binary and ternary inclusion complexes of cefuroxime axetil with β-cyclodextrin to improve its …

[PDF][PDF] AA comparative study of quality control testing on candesartan cilexetil conventional tablets in iraq

KTKA HAMRAH, AJN AL-SHAIBANI… - … Journal of Applied …, 2020 - researchgate.net
Objective: The present study was performed to compare the quality of conventional tablets
loaded with candesartan cilexetil. The selected candesartan cilexetil tablets were …

[PDF][PDF] Effect of natural and synthetic polymers on the properties of candesartan cilexetil matrix tablet prepared by dry granulation

OS Salih, RA Nief - Asian J Pharm Clin Res, 2016 - academia.edu
Objective: The objective of this study is to develop a controlled release matrix tablet of
candesartan cilexetil to reduce the frequency of administration, enhance bioavailability and …