Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Positron emission tomography (PET) is an important driver for present day healthcare.
Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview …

PET myocardial perfusion imaging (MPI) is increasingly being used for noninvasive
detection and evaluation of coronary artery disease. However, the widespread use of PET …

Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of
analyzing coronary artery disease (CAD) but subject to the various shortcomings of …

The growing discovery and development of novel radiopharmaceuticals and radiolabeling
methods requires an increasing capacity for radiochemistry experiments. However, such …

The mitochondrion's negatively charged membrane potential has been well documented to
drive the accumulation of membrane permeable delocalized lipophilic cations (DLC). DLC …

A series of fluoro-pegylated (FPEG) 2-pyridinylbenzoxazole and 2-pyridinylbenzothiazole
derivatives were synthesized and evaluated as novel β-amyloid (Aβ) imaging probes for …

Mitochondria-targeting positron emission tomography (PET) and fluorescent dual-modal
probes are rarely reported. As one of the most promising lipophilic cations, F16 and its …

Recently, we demonstrated the potential of a [18F]‐trimethylammonium BODIPY dye for
cardiac imaging. This is the first example of the use of the [18F]‐ammonium BODIPY dye for …

Cardiac positron emission tomography (PET) and positron emission tomography/computed
tomography (PET/CT) are encouraging precise non-invasive imaging modalities that allow …