Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration

Y Mikami, BR Grubb, TD Rogers, H Dang… - Science translational …, 2023 - science.org
Unlike solid organs, human airway epithelia derive their oxygen from inspired air rather than
the vasculature. Many pulmonary diseases are associated with intraluminal airway …

Intestinal in vitro transport assay combined with physiologically based kinetic modeling as a tool to predict bile acid levels in vivo

VMP De Bruijn, W Te Kronnie, IMCM Rietjens… - ALTEX-Alternatives to …, 2024 - altex.org
Bile acid homeostasis is vital for numerous metabolic and immune functions in humans. The
enterohepatic circulation of bile acids is extremely efficient, with~ 95% of intestinal bile acids …

Comparison of permeable cell culture inserts for use in culture of a human in vitro air–liquid interface model system

SA Brocke, AM Speen, S Masood… - Physiological …, 2024 - Wiley Online Library
In this study, we compared 12 mm cell culture inserts with permeable polyester membranes
(0.4 μm pores) from two different manufacturers: CELLTREAT® and Corning®. Physical …

慢性鼻窦炎人鼻黏膜原代细胞的培养与鉴定[综述]

李杭津, 王吉喆, 于申, 郭燕, 曲慧, 尹君婷 - 国际耳鼻咽喉头颈外科杂志, 2023 - entbjb.com
慢性鼻窦炎是耳鼻咽喉科常见的炎症性气道疾病. 鼻及鼻窦黏膜细胞接受环境刺激,
释放细胞因子, 在鼻腔, 鼻窦的炎症反应和免疫调节过程中发挥重要的协调作用 …

Regeneration and reuse of transwell-type culture inserts for blood-brain barrier modelling

M Shuvalova, G Nosov - Journal of Cellular Biotechnology - content.iospress.com
Culture inserts of Transwell type are widely used in laboratories worldwide to model non-
cerebral vessels, the bloodbrain barrier (BBB), and other blood-tissue barriers, and also for …

The Role of the Airway Epithelium in Particulate Matter-Induced Exacerbation of Respiratory Viral Infection

S Brocke - 2024 - search.proquest.com
Decades of air pollution research have substantially improved our understanding of the
dangers of this prevalent, sometimes seemingly innocuous, environmental toxicant. It is …