For many viruses, one or two proteins enable cell binding, membrane fusion and entry. The
large number of proteins employed by poxviruses is unprecedented and may be related to …

Myxoma virus is a poxvirus naturally found in two American leporid (rabbit) species
(Sylvilagus brasiliensis and Sylvilagus bachmani) in which it causes an innocuous localised …

Oncolytic viruses are one of the most promising novel therapeutics for malignant cancers.
They selectively infect and kill cancer cells while sparing the normal counterparts, expose …

A two-step, automated, high-throughput RNAi silencing screen was used to identify host cell
factors required during vaccinia virus infection. Validation and analysis of clustered hits …

Poxviruses are characterized by their large size, complex composition, and cytoplasmic life
cycle. They produce two types of infectious particles: mature virions (MVs) and extracellular …

For many viruses, one or two proteins allow cell attachment and entry, which occurs through
the plasma membrane or following endocytosis at low pH. In contrast, vaccinia virus (VACV) …

Viruses enter host cells via several mechanisms, including endocytosis, macropinocytosis,
and phagocytosis. They can also fuse at the plasma membrane and can spread within the …

We show that SAMD9 is an innate host antiviral stress response element that participates in
the formation of antiviral granules. Poxviruses, myxoma virus and vaccinia virus specifically …

Featuring contributions from specialists in related research areas, this book presents expert
summaries on state-of-the-art diagnostic approaches for major animal viral pathogens, with …

The use of oncolytic viruses for the treatment of cancer is an emerging field of cancer
research and therapy. Oncolytic viruses are designed to induce tumor specific immunity …