Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a
common chronic pain condition with major impact on quality of life. Examples include …

Trigeminal neuralgia is a very painful neurological condition with severe, stimulus-evoked,
short-lasting stabbing pain attacks in the face. The past decade has offered new insights into …

Temporomandibular disorders (TMD) are a group of musculoskeletal diseases affecting
masticatory muscles and temporomandibular joints (TMJ). In this context, the chronic TMD …

Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

Pre-diabetes and diabetes are a global epidemic, and the associated neuropathic
complications create a substantial burden on both the afflicted patients and society as a …

The redefinition of neuropathic pain as “pain arising as a direct consequence of a lesion or
disease affecting the somatosensory system,” which was suggested by the International …

Patients with neuropathic pain are heterogeneous in etiology, pathophysiology, and clinical
appearance. They exhibit a variety of painrelated sensory symptoms and signs (sensory …

Introduction Trigeminal neuralgia (TN) is characterized by touch-evoked unilateral brief
shock-like paroxysmal pain in one or more divisions of the trigeminal nerve. In addition to …

Allodynia (pain due to a stimulus that does not usually provoke pain) and hyperalgesia
(increased pain from a stimulus that usually provokes pain) are prominent symptoms in …