The substitution of primary or secondary alcohols with nucleophiles mediated by a redox
combination of a trialkylor triarylphosphine and a dialkyl azodicarboxylate is popularly …

The history and development of 4′-fluoro-nucleosides is discussed in this review. This is a
class of nucleosides which have their origin in the discovery of the rare fluorine containing …

Since its discovery 12 years ago, aminoethylglycyl peptide nucleic acid (aeg-PNA) has
emerged as one of the successful DNA mimics for potential therapeutic and diagnostic …

Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …

Fluorinated nucleosides and oligonucleotides are of specific interest as probes for studying
nucleic acids interaction, structures, biological transformations, and its biomedical …

This review briefly discussed nomenclature, synthesis, chemistry, and biophysical properties
of a plethora of PNA derivatives reported since the discovery of aeg PNA. Different synthetic …

During the latest decades a number of different nucleic acid analogs containing natural
nucleobases on a modified backbone have been synthesized. An example of this is peptide …

Fluoro‐olefin compounds, because of their favorable physicochemical properties, have
been used as key materials in the fields of medicinal chemistry, chemical biology, and …

We report herein a tandem reaction of para-quinone methides with TMSCF2Br to construct
bromofluoroalkenes in a Z-selective manner. While TMSCF2Br has been documented as the …

Peptide nucleic acid (PNA) is a nucleic acid analogue and a fully synthetic DNA/RNA-
recognising ligand with a neutral peptide-like backbone. In spite of the large change on the …