Over the past few decades, the development of potent and safe immune-activating adjuvant
technologies has become the heart of intensive research in the constant fight against highly …

Saponin-based vaccine adjuvants are potent in preclinical animal models and humans, but
their mechanisms of action remain poorly understood. Here, using a stabilized HIV envelope …

Current antigen delivery platforms, such as alum and nanoparticles, are not readily tunable,
thus may not generate optimal adaptive immune responses. We created an antigen delivery …

The induction of durable protective immune responses is the main goal of prophylactic
vaccines, and adjuvants play an important role as drivers of such responses. Despite …

Rare B cells can have special pathogen-recognition features giving them the potential to
make outsized contributions to protective immunity. However, rare naive B cells infrequently …

In this issue of Transplantation, Tunbridge et al1 presented a timely overview on some of the
negative immune suppressive mechanisms, focusing specifically on dendritic and myeloid …

Abstract Epstein Barr Virus (EBV) is an orally transmitted, γ-herpesvirus infecting 90% of
adults worldwide. Infection is associated with various cancers and development of multiple …