A Willemsen, MP Zwart - Virus Evolution, 2019 - academic.oup.com
Viruses are widely used as vectors for heterologous gene expression in cultured cells or natural hosts, and therefore a large number of viruses with exogenous sequences inserted …
T Kawagishi, L Sánchez-Tacuba… - Proceedings of the …, 2023 - National Acad Sciences
Rotaviruses (RVs) preferentially replicate in the small intestine and frequently cause severe diarrheal disease, and the following enteric infection generally induces variable levels of …
P Doldan, J Dai, C Metz-Zumaran, JT Patton… - Journal of …, 2022 - Am Soc Microbiol
Rotavirus infects intestinal epithelial cells and is the leading cause of gastroenteritis in infants worldwide. Upon viral infection, intestinal cells produce type I and type III interferons …
L Sánchez-Tacuba, N Feng, NJ Meade… - Journal of …, 2020 - Am Soc Microbiol
An entirely plasmid-based reverse genetics (RG) system was recently developed for rotavirus (RV), opening new avenues for in-depth molecular dissection of RV biology …
SL Nichols, EM Nilsson, H Brown-Harding… - Journal of …, 2023 - Am Soc Microbiol
Many viruses sequester the materials needed for their replication into discrete subcellular factories. For rotaviruses (RVs), these factories are called viroplasms, and they are formed in …
O Diebold, V Gonzalez, L Venditti, C Sharp… - Journal of …, 2022 - Am Soc Microbiol
Species A rotavirus (RVA) vaccines based on live attenuated viruses are used worldwide in humans. The recent establishment of a reverse genetics system for rotoviruses (RVs) has …
T Uprety, D Wang, F Li - Archives of virology, 2021 - Springer
Rotaviruses are segmented double-stranded RNA viruses with a high frequency of gene reassortment, and they are a leading cause of global diarrheal deaths in children less than 5 …
Rotavirus, a segmented double-stranded RNA virus of the Reoviridae family, is a primary cause of acute gastroenteritis in young children. In countries where rotavirus vaccines are …
Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in infants and the young of many economically important animals. Although vaccines against …