Interleukin 6 (IL-6) is a pleiotropic cytokine executing a diverse number of functions, ranging
from its effects on acute phase reactant pathways, B and T lymphocytes, blood brain barrier …

Psoriasis, a chronic inflammatory skin condition, is often accompanied by psychiatric
comorbidities such as anxiety, depression, suicidal ideation, and other mental disorders …

Background Obstructive sleep apnea (OSA) affects 10–26% of adults in the United States
with known sex differences in prevalence and severity. OSA is characterized by elevated …

Vascular pathology is associated with cognitive impairment in diseases such as type 1
diabetes; however, how capillary flow is affected and the underlying mechanisms remain …

The prenatal environment can alter neurodevelopmental and clinical trajectories, markedly
increasing risk for psychiatric disorders in childhood and adolescence. To understand if and …

Aging plays a pivotal role in the pathogenesis of cerebral small vessel disease (CSVD),
contributing to the onset and progression of vascular cognitive impairment and dementia …

Background Hepatic encephalopathy (HE) symptoms associated with liver insufficiency are
linked to the neurotoxic effects of ammonia and other toxic metabolites reaching the brain …

Content: The impact of triglyceride levels is important to understand the changes in
metabolism and structure. With an increase in obesity and hyperlipidemia due to diet; …

Long-term ischemia leads to insufficient cerebral microvascular perfusion and dysfunction.
Reperfusion restores physiological fluid shear stress (FSS) but leads to serious injury. The …