Biofilm of Candida albicans: formation, regulation and resistance

R Pereira, RO Dos Santos Fontenelle… - Journal of Applied …, 2021 - academic.oup.com
Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …

[HTML][HTML] Synthetic antimicrobial peptides: Characteristics, design, and potential as alternative molecules to overcome microbial resistance

PG Lima, JTA Oliveira, JL Amaral, CDT Freitas… - Life Sciences, 2021 - Elsevier
Recently, the dramatic emergence of antimicrobial resistance has received attention from
World Health Organization. Synthetic antimicrobial peptides (SAMPs) are considered new …

Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal

S Costa-de-Oliveira, AG Rodrigues - Microorganisms, 2020 - mdpi.com
Candida albicans represents the most frequent isolated yeast from bloodstream infections.
Despite the remarkable progress in diagnostic and therapeutic approaches, these infections …

Antifungal resistance and new strategies to control fungal infections

P Vandeputte, S Ferrari… - International journal of …, 2012 - Wiley Online Library
Despite improvement of antifungal therapies over the last 30 years, the phenomenon of
antifungal resistance is still of major concern in clinical practice. In the last 10 years the …

NLLSS: predicting synergistic drug combinations based on semi-supervised learning

X Chen, B Ren, M Chen, Q Wang… - PLoS computational …, 2016 - journals.plos.org
Fungal infection has become one of the leading causes of hospital-acquired infections with
high mortality rates. Furthermore, drug resistance is common for fungus-causing diseases …

Efflux-mediated antifungal drug resistance

RD Cannon, E Lamping, AR Holmes… - Clinical microbiology …, 2009 - Am Soc Microbiol
Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …

Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform

T Dai, BB Fuchs, JJ Coleman, RA Prates… - Frontiers in …, 2012 - frontiersin.org
Opportunistic fungal pathogens may cause superficial or serious invasive infections,
especially in immunocompromised and debilitated patients. Invasive mycoses represent an …

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

D Sanglard, A Coste, S Ferrari - FEMS yeast research, 2009 - academic.oup.com
Fungi are primitive eukaryotes and have adapted to a variety of niches during evolution.
Some fungal species may interact with other life forms (plants, insects, mammals), but are …

Trichophyton rubrum azole resistance mediated by a new ABC transporter, TruMDR3

M Monod, M Feuermann, K Salamin… - Antimicrobial agents …, 2019 - Am Soc Microbiol
The mechanisms of terbinafine resistance in a set of clinical isolates of Trichophyton rubrum
have been studied recently. Of these isolates, TIMM20092 also showed reduced sensitivity …

The role of eukaryotic and prokaryotic ABC transporter family in failure of chemotherapy

R El-Awady, E Saleh, A Hashim, N Soliman… - Frontiers in …, 2017 - frontiersin.org
Over the years chemotherapy failure has been a vital research topic as researchers have
been striving to discover reasons behind it. The extensive studies carried out on …