Transition-metal-catalyzed C–H bond arylation has recently emerged as a powerful tool for
the functionalization of organic molecules that may complement or even replace traditional …

The development of practical and efficient methods for C–C and C–X bond formation has
attracted a great deal of current attention with the advent of C–H functionalization reactions …

Site-selective radical reactions of benzylic C–H bonds are now highly effective methods for
C (sp3–H) functionalization and cross-coupling. The existing methods, however, are often …

Although metal-catalyzed direct arylation reactions of non-or weakly acidic C–H bonds have
recently received much attention, chemists have relied heavily on substrates with …

The direct transition-metal-catalyzed conversion of carboxylic acid groups into other C–C or
C–X bonds provides a complementary bond disconnection to traditional cross-coupling …

Aryl (di) azinyl ketones are very useful intermediates in the synthesis of pharmaceuticals,
such as antihistamines, antimalarials, antiarrhythmic agents, β2-adrenergic agonists, and …

A Lewis acid catalyzed benzylic C− H bond functionalization of alkyl-substituted azaarenes
is described. Sc (OTf) 3 and Y (OTf) 3 promoted the direct addition of alkyl-substituted …

A novel copper-catalyzed annulation of 2-alkylazaarenes with α, β-unsaturated carboxylic
acids has been accomplished. This reaction featuring C–H olefination and decarboxylative …

A highly efficient synthesis of trans-alkenylazaarene under catalyst-free conditions was
developed via the addition of methylazaarenes to N-sulfonyl aldimines and a subsequent C …

We have developed a Pd (II)-catalyzed oxidative tandem aminoalkylation via divergent C
(sp3)–H functionalization, affording three-and five-membered-ring fused indolines in good …