The frequently studied polysaccharide, chitosan oligosaccharide/chitooligosaccharide
(COS) is the major degradation product of chitosan/chitin via chemical hydrolysis or …

Chitosan oligosaccharide (COS) is an oligomer of β-(1➔ 4)-linked d-glucosamine. COS can
be prepared from the deacetylation and hydrolysis of chitin, which is commonly found in the …

Injectable thermosensitive hydrogel has been regarded as attractive drug delivery system,
which displays a sol-gel phase transition upon injection in response to temperature …

Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …

During the past decade we have witnessed the rapid development and understanding of
living radical polymerization (LRP)(or reversible deactivation radical polymerizations …

Gene-based therapies have emerged as a new modality for combating a myriad of currently
incurable diseases. However, the fragile nature of gene therapeutics has significantly …

Transfection by means of non-viral gene delivery vectors is the cornerstone of modern gene
delivery. Despite the resources poured into the development of ever more effective …

Gene therapy, which involves replacement of a defective gene with a functional, healthy
copy of that gene, is a potentially beneficial cancer treatment approach particularly over …

Gene therapy provides a promising strategy for curing monogenetic disorders and complex
diseases. However, there are challenges associated with the use of viral delivery vectors …

Nanotechnology-based gene delivery is the division of nanomedicine concerned with the
synthesis, characterization, and functionalization of nanomaterials to be used in targeted …