Multi-omics profiling approach to asthma: an evolving paradigm

Y Gautam, E Johansson, TB Mersha - Journal of personalized medicine, 2022 - mdpi.com
Asthma is a complex multifactorial and heterogeneous respiratory disease. Although
genetics is a strong risk factor of asthma, external and internal exposures and their …

Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework

AFA Mentis, E Dardiotis, GP Chrousos - Molecular Psychiatry, 2021 - nature.com
The potential existence and roles of the meningeal lymphatic system in normal and
pathological brain function have been a long-standing enigma. Recent evidence suggests …

Ten simple rules for carrying out and writing meta-analyses

DA Forero, S Lopez-Leon… - PLoS computational …, 2019 - journals.plos.org
In the context of evidence-based medicine, meta-analyses provide novel and useful
information [1], as they are at the top of the pyramid of evidence and consolidate previous …

An integrated bioinformatics analysis towards the identification of diagnostic, prognostic, and predictive key biomarkers for urinary bladder cancer

M Sarafidis, GI Lambrou, V Zoumpourlis, D Koutsouris - Cancers, 2022 - mdpi.com
Simple Summary Bladder cancer is evidently a challenge as far as its prognosis and
treatment are concerned. The investigation of potential biomarkers and therapeutic targets is …

[PDF][PDF] Understanding the molecular mechanisms of asthma through transcriptomics

HW Park, ST Weiss - Allergy, asthma & immunology …, 2020 - synapse.koreamed.org
The transcriptome represents the complete set of RNA transcripts that are produced by the
genome under a specific circumstance or in a specific cell. High-throughput methods …

Meta-analysis of gene expression data in adipose tissue reveals new obesity associated genes

Y Goutzelas, P Kontou, Z Mamuris, P Bagos… - Gene, 2022 - Elsevier
High-throughput transcriptomic and proteomic data like microarray data are deposited in
public databases such as Gene Expression Omnibus (GEO). Omics data integration and …

Investigating molecular determinants of cancer cell resistance to ionizing radiation through an integrative bioinformatics approach

HI Toy, G Karakülah, PI Kontou, H Alotaibi… - Frontiers in cell and …, 2021 - frontiersin.org
Eradication of cancer cells through exposure to high doses of ionizing radiation (IR) is a
widely used therapeutic strategy in the clinical setting. However, in many cases, cancer cells …

A convergent functional genomics analysis to identify biological regulators mediating effects of creatine supplementation

DA Bonilla, Y Moreno, ES Rawson, DA Forero… - Nutrients, 2021 - mdpi.com
Creatine (Cr) and phosphocreatine (PCr) are physiologically essential molecules for life,
given they serve as rapid and localized support of energy-and mechanical-dependent …

Convergent functional genomics of cocaine misuse in humans and animal models

DA Forero, Y González-Giraldo - The American journal of drug and …, 2020 - Taylor & Francis
ABSTRACT Background: Data from the Global Burden of Disease Study 2016 recently
estimated that after opioid and cannabis use disorders, cocaine use disorders were among …

Integration of Antioxidant Activity Assays Data of Stevia Leaf Extracts: A Systematic Review and Meta-Analysis

M Papaefthimiou, PI Kontou, PG Bagos, GG Braliou - Antioxidants, 2024 - mdpi.com
Stevia rebaudiana Bertoni, a no-calorie natural sweetener, contains a plethora of
polyphenols that exert antioxidant properties with potential medicinal significance. Due to …